Biomedical research is undergoing a paradigm shift towards approaches centred on human
disease models owing to the notoriously high failure rates of the current drug development …

Metabolic diseases, including obesity, diabetes mellitus and cardiovascular disease, are a
major threat to health in the modern world, but efforts to understand the underlying …

Cellular models have created opportunities to explore the characteristics of human diseases
through well-established protocols, while avoiding the ethical restrictions associated with …

Natural compounds have diverse structures and are present in different forms of life.
Metabolites such as tannins, anthocyanins, and alkaloids, among others, serve as a defense …

Abstract Microplastics and Nanoplastics (MNPLs) pollution has been recognized as the
important environmental pollution caused by human activities in addition to global warming …

Neurotoxicity studies aim at understanding the toxic effects and mechanisms of toxicants to
human central nervous systems (CNS). However, human brains are the most complex …

Silver nanoparticles (AgNPs) are used in various research fields. Although the neurotoxicity
of AgNPs has been explored in animal models and 2D cell-culture models, including human …

In vitro modelling the complex (patho‐) physiological conditions of the heart is a major
challenge in cardiovascular research. In recent years, methods based on three‐dimensional …

Introduction Chemodynamic therapy (CDT) holds great promise in achieving cancer therapy
through Fenton and Fenton-like reactions, which generate highly toxic reactive species …

Neurological disorders are the second cause of death and the leading cause of disability
worldwide. Unfortunately, no cure exists for these disorders, but the actual therapies are only …