MSCs products as well as their derived extracellular vesicles, are currently being explored
as advanced biologics in cell-based therapies with high expectations for their clinical use in …

Wound healing is a complex but a fine‐tuned biological process in which human skin has
the ability to regenerate itself following damage. However, in particular conditions such as …

Cell‐based regenerative therapies, based on in vitro propagation of stem cells, offer
tremendous hope to many individuals suffering from degenerative diseases that were …

Since the 1960s and the therapeutic use of hematopoietic stem cells of bone marrow origin,
there has been an increasing interest in the study of undifferentiated progenitors that have …

In this paper, a pilot production process for mesenchymal stem/stromal freeze-dried
secretome was performed in a validated good manufacturing practice (GMP)-compliant cell …

Background The use of mesenchymal stem cells (MSCs) in research and in regenerative
medicine has progressed. Bone marrow as a source has drawbacks because of subsequent …

Stem cell-based therapies for repair and regeneration of different tissues are becoming
more important in the treatment of several diseases. Adult stem cells currently symbolize the …

Background The applications for fat grafting have increased recently, within both
regenerative and reconstructive surgery. Although fat harvesting, processing and injection …

It has been demonstrated that the biological effector of mesenchymal stem/stromal cells
(MSCs) is their secretome, which is composed of a heterogeneous pool of bioactive …

Mesenchymal stem cells (MSCs) were first isolated more than 50 years ago from the bone
marrow. Currently MSCs may also be isolated from several alternative sources and they …