CD44 is a transmembrane glycoprotein. When the CD44 gene is expressed, its pre-
messenger RNA (mRNA) can be alternatively spliced into mature mRNAs that encode …

The 'cancer stem cell'hypothesis has pointed to a specific target for new cancer therapies.
The hypothesis is based on the observation that only the 'cancer stem cell'among the other …

The human gut is host to almost 3000 microbial species, of which 90% are bacteria. Quorum
sensing (QS) molecules generated by intestinal bacteria are important in establishing …

Quorum sensing peptides (QSP) are an important class of bacterial peptides which can have
an effect on human host cells. These peptides are used by bacteria to communicate with …

Modern research into carcinogenesis has undergone three phases. Surgeons and
pathologists started the first phase roughly 250 years ago, establishing morphological traits …

It has been proposed that many human cancers are generated by intrinsic mechanisms that
produce “Bad Luck” mutations by the proliferation of organ-specific adult stem cells. There …

Developing rapidly from the cecal diverticulum in a 5-week-old embryo, the cecum, which is
developed from the caudal limb of the midgut loop, is different from the ascending colon. The …

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Solving the problem of preventing or treating cancers is still a major problem. While much is
known about those multi-disciplinary contributors to the initiation, promotion and progression …

The two hypotheses of the origin of cancer are the “stem cell” hypothesis and the
“Dedifferentiation” or “Re-programming” hypothesis. Cancers are derived from a single cell …