Marmoset models commonly used in biomedical research

K Mansfield - Comparative medicine, 2003 - ingentaconnect.com
The common marmoset (Callithrix jacchus) is a small, nonendangered New World primate
that is native to Brazil and has been used extensively in biomedical research. Historically the …

Advanced MRI and staging of multiple sclerosis lesions

M Absinta, P Sati, DS Reich - Nature Reviews Neurology, 2016 - nature.com
Over the past few decades, MRI-based visualization of demyelinated CNS lesions has
become pivotal to the diagnosis and monitoring of multiple sclerosis (MS). In this Review, we …

Air pollution, cognitive deficits and brain abnormalities: a pilot study with children and dogs

L Calderón-Garcidueñas, A Mora-Tiscareño… - Brain and …, 2008 - Elsevier
Exposure to air pollution is associated with neuroinflammation in healthy children and dogs
in Mexico City. Comparative studies were carried out in healthy children and young dogs …

[HTML][HTML] Animal models of multiple sclerosis: the good, the bad and the bottom line

RM Ransohoff - Nature neuroscience, 2012 - nature.com
Multiple sclerosis (MS) is a spontaneous, acquired, inflammatory demyelinating disease of
the human CNS. Because it involves a complex interaction between two of the most intricate …

[HTML][HTML] Diffusion tensor imaging of post mortem multiple sclerosis brain

K Schmierer, CAM Wheeler-Kingshott, PA Boulby… - Neuroimage, 2007 - Elsevier
Magnetic resonance imaging (MRI) is being used to probe the central nervous system (CNS)
of patients with multiple sclerosis (MS), a chronic demyelinating disease. Conventional T2 …

Remyelinated lesions in multiple sclerosis: magnetic resonance image appearance

F Barkhof, W Brück, CJA De Groot, E Bergers… - Archives of …, 2003 - jamanetwork.com
Background Various types of pathologic mechanisms in multiple sclerosis (MS) can alter
magnetic resonance imaging (MRI) signals, and the appearance of remyelinated lesions on …

Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis

JR Wujek, C Bjartmar, E Richer… - … of Neuropathology & …, 2002 - academic.oup.com
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS). Most patients undergo an initial relapsing-remitting (RR-MS) course that …

Magnetization transfer and multicomponent T2 relaxation measurements with histopathologic correlation in an experimental model of MS

PJ Gareau, BK Rutt, SJ Karlik… - Journal of Magnetic …, 2000 - Wiley Online Library
Magnetization transfer and multicomponent T2 imaging techniques were implemented to
study guinea pig in vivo. A chronic‐progressive model of experimental allergic …

Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: a case for antigen‐specific antibody mediation

CS Raine, B Cannella, SL Hauser… - Annals of …, 1999 - Wiley Online Library
Neuropathological and ultrastructural features of central nervous system demyelination were
compared in marmoset experimental autoimmune encephalomyelitis (EAE) induced with …

TLR4 contributes to disease-inducing mechanisms resulting in central nervous system autoimmune disease

SM Kerfoot, EM Long, MJ Hickey… - The Journal of …, 2004 - journals.aai.org
Environmental factors strongly influence the development of autoimmune diseases,
including multiple sclerosis. Despite this clear association, the mechanisms through which …