Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Skeletal muscle is one of the most dynamic and plastic tissues of the human body. In
humans, skeletal muscle comprises approximately 40% of total body weight and contains 50 …

Skeletal muscle and adipose tissue are the two largest organs in the body. Skeletal muscle
is an effector organ, and adipose tissue is an organ that stores energy; in addition, they are …

Semi-quantification of proteins using Western blots typically involves normalization against
housekeeping genes such as β-actin. More recently, Ponceau S and Coomassie blue …

During aging, muscle gradually undergoes sarcopenia, the loss of function associated with
loss of mass, strength, endurance, and oxidative capacity. However, the 3D structural …

For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

The conversion of skeletal muscle fiber from fast twitch to slow‐twitch is important for
sustained and tonic contractile events, maintenance of energy homeostasis, and the …

The incidence and recurrence of hamstrings injuries are very high in sports, posing elevated
performance and financial-related costs. Attempts to identify the risk factors involved in …

Reference proteins (RP) or the total protein (TP) loaded is used to correct for uneven loading
and/or transfer in Western blotting. However, the signal sensitivity and the influence of …

Skeletal muscle myosin heavy chain (MyHC) fiber type composition is a critical determinant
of overall muscle function and health. Various approaches interrogate fiber type at the single …