Tuberculosis (TB) is a health threat to the global population. Anti-TB drugs and vaccines are
key approaches for TB prevention and control. TB animal models are basic tools for …

The terms “genotype” and “phenotype” were coined by the botanist and geneticist Wilhelm
Johannsen at the beginning of the 20th century (1). Both words have a Greek etymology …

Tuberculosis (TB) disease is a global epidemic caused by the pathogenic Mycobacterium
tuberculosis (Mtb). Tools that can track the replication status of viable Mtb cells within …

The efficacy of phages in multispecies infections has been poorly examined. The in vitro lytic
efficacies of phage cocktails AB-SA01, AB-PA01, which target Staphylococcus aureus and …

The pathogenesis of Mycobacterium tuberculosis (Mtb) is intrinsically linked to its intimate
and enduring interaction with its host, and understanding Mtb–host interactions at a …

Peptide design and drug development offer a promising solution for combating serious
diseases or infections. In this study, using an AI–human negotiation approach, we have …

4-N, N-Dimethylamino-1, 8-naphthalimide conjugate of trehalose (DMN-Tre) is a fluorogenic
dye recently developed as a diagnostic tool for tuberculosis. DMN-Tre selectively labels the …

Reporter strains have proven to be powerful tools to study Mycobacterium tuberculosis (Mtb)
physiology. Transcriptional and translational reporter strains are engineered by fusing a …

Screening strategies for antituberculosis compounds using Mycobacterium tuberculosis are
time consuming and require biosafety level 3 (BSL3) facilities, which makes the …

Mycobacterium tuberculosis resides in the lungs in various lesion types with unique
microenvironmental conditions. This diversity is in line with heterogeneous disease …