Mood disorders are associated with elevated inflammation, and the reduction of symptoms
after multiple treatments is often accompanied by pro-inflammation restoration. A variety of …

One in three adults with major depressive disorder (MDD) do not experience clinically
significant improvement after multiple sequential courses of antidepressants and have …

Reward devaluation theory posits that depressed individuals avoid and devalue positivity,
suggesting that they may hold fewer positive self-schemas. Previous meta-analytic reviews …

The microbiota-gut-brain axis (MGBA) refers to the bidirectional communication between the
brain and the gut microbiota and recent studies have linked the MGBA to health and …

Major depressive disorder (MDD) is an often chronic and/or recurrent disorder that is
associated with dysfunctions in multiple aspects of life including work and non-workrelated …

Depression, either bipolar or unipolar, is a highly prevalent and disabling condition. Even
though several treatment options exist for depressed patients, a significant portion of …

Neurotechnologies that measure and modulate brain activity have not yet reached
widespread clinical relevance. To accelerate translation into patient care, we propose three …

Repetitive negative thinking (RNT) is a transdiagnostic symptom associated with poor
outcomes in major depressive disorder (MDD). MDD is characterized by altered …

Major depression is a common and often disabling illness with significant morbidity and
mortality. In 2019, the 12-month prevalence of major depression in US adults was estimated …

Transcranial magnetic stimulation (TMS) is an FDA-approved neuromodulation treatment for
major depressive disorder (MDD), thought to work by altering dysfunctional brain …