The innate immune system initiates cell death pathways in response to pathogens and
cellular stress. Cell death can be either non-lytic (apoptosis) or lytic (PANoptosis, pyroptosis …

Cell death can be executed through distinct subroutines. PANoptosis is a unique
inflammatory cell death modality involving the interactions between pyroptosis, apoptosis …

Colorectal cancer (CRC) at advanced stages is rarely curable, underscoring the importance
of exploring the mechanism of CRC progression and invasion. NOD-like receptor family …

The COVID-19 pandemic was caused by the recently emerged β-coronavirus SARS-CoV-2.
SARS-CoV-2 has had a catastrophic impact, resulting in nearly 7 million fatalities worldwide …

Nucleotide-binding oligomerization domain (NOD)-like receptors, also known as nucleotide-
binding leucine-rich repeat receptors (NLRs), are a family of cytosolic pattern recognition …

The innate immune system provides the first line of defense against pathogens and cellular
insults and is activated by pattern recognition receptors sensing pathogen-or damage …

Inflammasomes are molecular scaffolds that are activated by damage-associated and
pathogen-associated molecular patterns and form a key element of innate immune …

Inflammasome activation is exclusively involved in sensing activation of innate immunity and
inflammatory response during viral infection. Accumulating evidence suggests that the …

Pyroptosis, apoptosis, and necroptosis are mainly programmed cell death (PCD) pathways
for host defense and homeostasis. PANoptosis is a newly distinct inflammatory PCD …

Regulated cell death (RCD) is considered a critical pathway in cancer therapy, contributing
to eliminating cancer cells and influencing treatment outcomes. The application of RCD in …