Association between MTHFR gene C677T polymorphism and gestational diabetes mellitus in Chinese population: a meta-analysis

X Tan, H Chen - Frontiers in Endocrinology, 2023 - frontiersin.org
Background and purpose The relationship of the methylenetetrahydrofolate reductase
(MTHFR) gene C677T polymorphism with the incidence of gestational diabetes mellitus …

SARS-CoV-2 infection: what is currently known about homocysteine involvement?

N Filip, E Cojocaru, OV Badulescu, A Clim, AC Pinzariu… - Diagnostics, 2022 - mdpi.com
Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
spread rapidly throughout the world causing health, social and economic instability. The …

MTHFR 677TT is associated with decreased number of embryos and cumulative live birth rate in patients undergoing GnRHa short protocol: a retrospective study

H Zeng, Z Liu, L Zhang, N Liu - BMC Pregnancy and Childbirth, 2022 - Springer
Abstract Background Whether MTHFR C677T genotype affects pregnancy outcomes
following assisted reproductive technology is conflicting. And the role of MTHFR C677T …

The Role of One-Carbon Metabolism and Methyl Donors in Medically Assisted Reproduction: A Narrative Review of the Literature

K Sfakianoudis, A Zikopoulos, S Grigoriadis… - International Journal of …, 2024 - mdpi.com
One-carbon (1-C) metabolic deficiency impairs homeostasis, driving disease development,
including infertility. It is of importance to summarize the current evidence regarding the …

Association of paternal MTHFR polymorphisms (C677T) with clinical outcomes in ICSI treatment

Y Wan, W Liu, B Xu, X Jiang, J Hua - Frontiers in Endocrinology, 2022 - frontiersin.org
Purpose This study aims to investigate the association between paternal
methylenetetrahydrofolate reductase (MTHFR) polymorphisms (C677T) and embryonic …

Drug substitution and adjuvant therapy in patients with genetics related infertility: A review

J Zhu, J Jin, Q Qi, Q Zhou, J Zhou… - Drug Discoveries & …, 2023 - jstage.jst.go.jp
With the in-depth study of the human genome and the increasing popularity of gene
sequencing, it has been gradually confirmed that genetics can play a crucial role in infertility …

[PDF][PDF] The influence of paternal MTHFR C677T polymorphism on in vitro fertilization outcomes in male Han population

Y Wan, X Chen, X Song, S Li, J Hua - Journal of Men's Health, 2024 - oss.jomh.org
The methylenetetrahydrofolate reductase (MTHFR) regulates the metabolism of
homocysteine in the human body, and MTHFR C677T polymorphism is correlated with male …

[PDF][PDF] Association of Methylenetetrahydrofolate Reductase Gene Polymorphism C677T with Oocyte Number and Embryo Quality in Iraqi Infertile Women Undergoing …

RZ Al-Yasiry, MA Jawad, MS Abbood - Al-Rafidain Journal of Medical …, 2024 - iasj.net
Abstract Background: Methylenetetrahydrofolate reductase (MTHFR) C677T is a single
nucleotide polymorphism (SNP) that affects the production of 5-methyltetrahydrofolate (5 …

Serum homocysteine level is an independent risk factor for embryo quality in advanced infertility patient with diminished ovarian reserve: a large sample retrospective …

J Li, H Wang, L Sun, J Li, D Cao, X Zhao, X He, Y Jiang… - 2022 - researchsquare.com
Backgrounds: Diminished ovarian reserve (DOR) contributes significantly to female infertility.
And embryo quality is one of the decisive factors in the success of pregnancy. However, the …