[HTML][HTML] Anti-obesity drug discovery: advances and challenges
Enormous progress has been made in the last half-century in the management of diseases
closely integrated with excess body weight, such as hypertension, adult-onset diabetes and …
closely integrated with excess body weight, such as hypertension, adult-onset diabetes and …
Sarcopenia and cardiovascular diseases
AA Damluji, M Alfaraidhy, N AlHajri, NN Rohant… - Circulation, 2023 - Am Heart Assoc
Sarcopenia is the loss of muscle strength, mass, and function, which is often exacerbated by
chronic comorbidities including cardiovascular diseases, chronic kidney disease, and …
chronic comorbidities including cardiovascular diseases, chronic kidney disease, and …
Functions of interoception: From energy regulation to experience of the self
We review recent work on the functions of interoceptive processing, by which the nervous
system anticipates, senses, and integrates signals originating from the body. We focus on …
system anticipates, senses, and integrates signals originating from the body. We focus on …
Function and mechanisms of enteroendocrine cells and gut hormones in metabolism
FM Gribble, F Reimann - Nature Reviews Endocrinology, 2019 - nature.com
Gut hormones have many key roles in the control of metabolism, as they target diverse
tissues involved in the control of intestinal function, insulin secretion, nutrient assimilation …
tissues involved in the control of intestinal function, insulin secretion, nutrient assimilation …
The ups and downs of caloric restriction and fasting: from molecular effects to clinical application
SJ Hofer, D Carmona‐Gutierrez, MI Mueller… - EMBO Molecular …, 2022 - embopress.org
Age‐associated diseases are rising to pandemic proportions, exposing the need for efficient
and low‐cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and …
and low‐cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and …
[HTML][HTML] Anxiety, depression, and the microbiome: a role for gut peptides
The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …
The association of periodontal diseases with metabolic syndrome and obesity
S Jepsen, J Suvan, J Deschner - Periodontology 2000, 2020 - Wiley Online Library
Periodontitis is a multifactorial chronic inflammatory disease associated with dysbiotic
plaque biofilms and characterized by progressive destruction of the tooth‐supporting …
plaque biofilms and characterized by progressive destruction of the tooth‐supporting …
[HTML][HTML] Novel agents for the pharmacological treatment of alcohol use disorder
Alcohol use disorder (AUD) is a highly prevalent but severely under-treated disorder, with
only three widely-approved pharmacotherapies. Given that AUD is a very heterogeneous …
only three widely-approved pharmacotherapies. Given that AUD is a very heterogeneous …
[HTML][HTML] Toward a wiring diagram understanding of appetite control
ML Andermann, BB Lowell - Neuron, 2017 - cell.com
Prior mouse genetic research has set the stage for a deep understanding of appetite
regulation. This goal is now being realized through the use of recent technological …
regulation. This goal is now being realized through the use of recent technological …
Ghrelin, CCK, GLP-1, and PYY (3–36): secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB
The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …
management of obesity and type 2 diabetes mellitus and novel developments in …