Idiopathic REM sleep behaviour disorder and neurodegeneration—an update
So-called idiopathic rapid eye movement (REM) sleep behaviour disorder (RBD), formerly
seen as a rare parasomnia, is now recognized as the prodromal stage of an α …
seen as a rare parasomnia, is now recognized as the prodromal stage of an α …
Motor and non-motor circuit disturbances in early Parkinson disease: which happens first?
For the last two decades, pathogenic concepts in Parkinson disease (PD) have revolved
around the toxicity and spread of α-synuclein. Thus, α-synuclein would follow caudo-rostral …
around the toxicity and spread of α-synuclein. Thus, α-synuclein would follow caudo-rostral …
Control of sleep and wakefulness
This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …
Wakefulness promoting systems cause low-voltage, fast activity in the …
[HTML][HTML] The microstructure of REM sleep: Why phasic and tonic?
Rapid eye movement (REM) sleep is a peculiar neural state that occupies 20–25% of
nighttime sleep in healthy human adults and seems to play critical roles in a variety of …
nighttime sleep in healthy human adults and seems to play critical roles in a variety of …
What is REM sleep?
For many decades, sleep researchers have sought to determine which species 'have'rapid
eye movement (REM) sleep. In doing so, they relied predominantly on a template derived …
eye movement (REM) sleep. In doing so, they relied predominantly on a template derived …
Forward-genetics analysis of sleep in randomly mutagenized mice
H Funato, C Miyoshi, T Fujiyama, T Kanda, M Sato… - Nature, 2016 - nature.com
Sleep is conserved from invertebrates to vertebrates, and is tightly regulated in a
homeostatic manner. The molecular and cellular mechanisms that determine the amount of …
homeostatic manner. The molecular and cellular mechanisms that determine the amount of …
[HTML][HTML] The energy allocation function of sleep: a unifying theory of sleep, torpor, and continuous wakefulness
MH Schmidt - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
The energy allocation (EA) model defines behavioral strategies that optimize the temporal
utilization of energy to maximize reproductive success. This model proposes that all species …
utilization of energy to maximize reproductive success. This model proposes that all species …
Descending command neurons in the brainstem that halt locomotion
The episodic nature of locomotion is thought to be controlled by descending inputs from the
brainstem. Most studies have largely attributed this control to initiating excitatory signals, but …
brainstem. Most studies have largely attributed this control to initiating excitatory signals, but …
REM sleep behavior disorder: diagnosis, clinical implications, and future directions
EK St Louis, BF Boeve - Mayo Clinic Proceedings, 2017 - Elsevier
Rapid eye movement sleep behavior disorder (RBD) is diagnosed by a clinical history of
dream enactment accompanied by polysomnographic rapid eye movement sleep atonia …
dream enactment accompanied by polysomnographic rapid eye movement sleep atonia …
A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series …
L Sabater, C Gaig, E Gelpi, L Bataller… - The Lancet …, 2014 - thelancet.com
Background Autoimmunity might be associated with or implicated in sleep and
neurodegenerative disorders. We aimed to describe the features of a novel neurological …
neurodegenerative disorders. We aimed to describe the features of a novel neurological …