Bioactive species, including reactive oxygen species (ROS, including O2˙−, H2O2, HOCl,
1O2,˙ OH, HOBr, etc.), reactive nitrogen species (RNS, including ONOO−, NO, NO2, HNO …

Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …

All forms of life have absolute request for metal elements, because metal elements are
instrumental in various fundamental processes. Fluorescent probes have been widely used …

Fluorescence sensing can not only identify a target substrate qualitatively but also achieve
the purpose of quantitative detection through the change of the fluorescence signal. It has …

Near-infrared (NIR) fluorescence imaging technique is garnering increasing research
attention due to various advantages. However, most NIR fluorescent probes still suffer from a …

Fluorescent probes for biothiols have aroused increasing interest owing to their potential to
enable better understanding of the diverse physiological and pathological processes related …

Photodynamic therapy is considered as a promising treatment for cancer, but still faces
several challenges. The hypoxic environment in solid tumors, imprecise tumor recognition …

The ultimate goal of cancer therapy is to eliminate malignant tumors while causing no
damage to normal tissues. In the past decades, numerous nanoagents have been employed …

Characterizing metabolism in cancer is crucial for understanding tumor biology and for
developing potential therapies. Although most metabolic investigations analyze averaged …

RNA interference (RNAi) has proved to be a promising modality for disease treatment.
However, the promise of conventional RNA therapeutics for clinical application is severely …