Next-generation sequencing supports targeted antibiotic treatment for culture negative orthopedic infections
The isolation of an infective pathogen can be challenging in some patients with active,
clinically apparent infectious diseases. Despite efforts in the microbiology lab to improve the …
clinically apparent infectious diseases. Despite efforts in the microbiology lab to improve the …
Perioperative antibiotic prophylaxis in total joint arthroplasty: a systematic review and meta-analysis
Background: The 2017 US Centers for Disease Control and Prevention (CDC) guidelines for
the prevention of surgical site infection (SSI) recommended against continuation of …
the prevention of surgical site infection (SSI) recommended against continuation of …
[HTML][HTML] Culture-negative periprosthetic joint infection: an update on what to expect
TL Tan, MM Kheir, N Shohat, DD Tan, M Kheir… - JBJS Open …, 2018 - journals.lww.com
Background: Culture-negative periprosthetic joint infection (PJI) is a challenging condition to
treat. The most appropriate management of culture-negative PJI is not known, and there is …
treat. The most appropriate management of culture-negative PJI is not known, and there is …
Novel insights into Staphylococcus aureus deep bone infections: the involvement of osteocytes
Periprosthetic joint infection (PJI) is a potentially devastating complication of orthopedic joint
replacement surgery. PJI with associated osteomyelitis is particularly problematic and …
replacement surgery. PJI with associated osteomyelitis is particularly problematic and …
Diagnosis and treatment of culture-negative periprosthetic joint infection
Identification of the causative organism (s) in periprosthetic joint infection (PJI) is a
challenging task. The shortcomings of traditional cultures have been emphasized in recent …
challenging task. The shortcomings of traditional cultures have been emphasized in recent …
What is the long-term economic societal effect of periprosthetic infections after THA? A Markov analysis
TJ Parisi, JF Konopka, HS Bedair - Clinical Orthopaedics and …, 2017 - journals.lww.com
Background Current estimates for the direct costs of a single episode of care for
periprosthetic joint infection (PJI) after THA are approximately USD 100,000. These …
periprosthetic joint infection (PJI) after THA are approximately USD 100,000. These …
[HTML][HTML] Prevention of periprosthetic joint infection (PJI): a clinical practice protocol in high-risk patients
Background: Periprosthetic joint infection (PJI) represents 25% of failed total knee
arthroplasties (TKA). The European Knee Associates (EKA) formed a transatlantic panel of …
arthroplasties (TKA). The European Knee Associates (EKA) formed a transatlantic panel of …
[HTML][HTML] Next generation sequencing for pathogen detection in periprosthetic joint infections
PF Indelli, S Ghirardelli, B Violante… - EFORT Open …, 2021 - eor.bioscientifica.com
Periprosthetic joint infections (PJI) represent one of the most catastrophic complications
following total joint arthroplasty (TJA). The lack of standardized diagnostic tests and …
following total joint arthroplasty (TJA). The lack of standardized diagnostic tests and …
The AAHKS clinical research award: extended oral antibiotics prevent periprosthetic joint infection in high-risk cases: 3855 patients with 1-year follow-up
Background Surgical and host factors predispose patients to periprosthetic joint infection
(PJI) after primary total hip arthroplasty (THA) and total knee arthroplasty (TKA). While …
(PJI) after primary total hip arthroplasty (THA) and total knee arthroplasty (TKA). While …
Revision knee replacement for prosthetic joint infection: Epidemiology, clinical outcomes and health-economic considerations
Prosthetic joint infection (PJI) is a devastating complication of knee replacement surgery.
Recent evidence has shown that the burden of disease is increasing as more and more …
Recent evidence has shown that the burden of disease is increasing as more and more …