A review of emerging technologies enabling improved solid oral dosage form manufacturing and processing

MS Arshad, S Zafar, B Yousef, Y Alyassin, R Ali… - Advanced drug delivery …, 2021 - Elsevier
Tablets are the most widely utilized solid oral dosage forms because of the advantages of
self-administration, stability, ease of handling, transportation, and good patient compliance …

PAT implementation for advanced process control in solid dosage manufacturing–A practical guide

S Sacher, J Poms, J Rehrl, JG Khinast - International Journal of …, 2022 - Elsevier
The implementation of continuous pharmaceutical manufacturing requires advanced control
strategies rather than traditional end product testing or an operation within a small range of …

Integrated continuous pharmaceutical technologies—a review

A Domokos, B Nagy, B Szilagyi, G Marosi… - … Process Research & …, 2021 - ACS Publications
Innovation in the pharmaceutical industry has been limited for a long time to the research
and development of new active compounds; meanwhile, the structure of the production …

Handbook of pharmaceutical granulation technology

DM Parikh - Drugs and the pharmaceutical sciences, 2005 - api.taylorfrancis.com
Since the Handbook of Pharmaceutical Granulation Technology, first and second editions,
were published, there have been rapid developments in the science of granulation, particle …

[HTML][HTML] A case study on decentralized manufacturing of 3D printed medicines

I Seoane-Viano, X Xu, JJ Ong, A Teyeb… - International Journal of …, 2023 - Elsevier
Abstract Pharmaceutical 3D printing (3DP) is one of the emerging enabling technologies of
personalised medicines as it affords the ability to fabricate highly versatile dosage forms. In …

Using residence time distribution in pharmaceutical solid dose manufacturing–A critical review

P Bhalode, H Tian, S Gupta, SM Razavi… - International journal of …, 2021 - Elsevier
While continuous manufacturing (CM) of pharmaceutical solid-based drug products has
been shown to be advantageous for improving the product quality and process efficiency in …

Challenges, opportunities and recent advances in near infrared spectroscopy applications for monitoring blend uniformity in the continuous manufacturing of solid oral …

NL Velez, JK Drennen, CA Anderson - International Journal of …, 2022 - Elsevier
Near infrared (NIR) spectroscopy has been widely recognized as a powerful PAT tool for
monitoring blend uniformity in continuous manufacturing (CM) processes. However, the …

Evaluation of the influence of material properties and process parameters on granule porosity in twin-screw wet granulation

M Peeters, AAB Jiménez, K Matsunami… - International Journal of …, 2023 - Elsevier
In recent years, continuous twin-screw wet granulation (TSWG) is gaining increasing interest
from the pharmaceutical industry. Despite the many publications on TSWG, only a limited …

Continuous twin screw granulation: A review of recent progress and opportunities in formulation and equipment design

C Portier, C Vervaet, V Vanhoorne - Pharmaceutics, 2021 - mdpi.com
Continuous twin screw wet granulation is one of the key continuous manufacturing
technologies that have gained significant interest in the pharmaceutical industry as well as …

Additive manufacturing of oral tablets: technologies, materials and printed tablets

A Abaci, C Gedeon, A Kuna, M Guvendiren - Pharmaceutics, 2021 - mdpi.com
Additive manufacturing (AM), also known as three-dimensional (3D) printing, enables
fabrication of custom-designed and personalized 3D constructs with high complexity in …