VEGF signaling: Role in angiogenesis and beyond

P Shaw, SKD Dwivedi, R Bhattacharya… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Angiogenesis is a crucial process for tissue development, repair, and tumor survival.
Vascular endothelial growth factor (VEGF) is a key driver secreted by cancer cells …

Sulforaphane's multifaceted potential: From neuroprotection to anticancer action

RA Otoo, AR Allen - Molecules, 2023 - mdpi.com
Sulforaphane (SFN) is a naturally occurring compound found in cruciferous vegetables such
as broccoli and cauliflower. It has been widely studied for its potential as a neuroprotective …

The role of ABCC10/MRP7 in anti-cancer drug resistance and beyond

DQ Chen, Y Xie, LQ Cao, JS Fleishman, Y Chen… - Drug Resistance …, 2024 - Elsevier
Abstract Multidrug resistance protein 7 (MRP7), also known as ATP-binding cassette (ABC)
transporter subfamily C10 (ABCC10), is an ABC transporter that was first identified in 2001 …

Exosomal circRNAs: Novel biomarkers and therapeutic targets for urinary tumors

Q Liu, S Li - Cancer Letters, 2024 - Elsevier
Exosomal circRNAs have emerged as promising biomarkers and therapeutic targets for
urinary tumors. In this review, we explored the intricate role of exosomal circRNAs in …

Targeting vascular normalization: a promising strategy to improve immune–vascular crosstalk in cancer immunotherapy

C Qian, C Liu, W Liu, R Zhou, L Zhao - Frontiers in Immunology, 2023 - frontiersin.org
Blood vessels are a key target for cancer therapy. Compared with the healthy vasculature,
tumor blood vessels are extremely immature, highly permeable, and deficient in pericytes …

Identification of disulfidptosis-related subtypes and development of a prognosis model based on stacking framework in renal clear cell carcinoma

K Peng, N Wang, Q Liu, L Wang, X Duan, G Xie… - Journal of Cancer …, 2023 - Springer
Background Clear cell renal cell carcinoma (ccRCC) is a common malignant tumor with an
unsatisfactory prognosis. This study aims to identify the expression patterns of disulfidptosis …

The roles of ERIANIN in tumor and innate immunity and its' perspectives in immunotherapy

Z Yang, R Liu, M Qiu, H Mei, J Hao, T Song… - Frontiers in …, 2023 - frontiersin.org
Traditional Chinese medicine has been used in China for thousands of years. In 2022, the
14th Five-Year Plan for the Development of Traditional Chinese Medicine was released …

Flexible Plasmonic Paper Substrates as Surface-Enhanced Raman Scattering (SERS) Biosensors Enable Sensitive Detection of Sunitinib Malate Drug

M Esmati, N Hajari, V Eskandari - Plasmonics, 2024 - Springer
Sunitinib malate (SM) is a chemical compound belonging to the class of kinase inhibitors
and is mainly used in cancer treatment. However, despite its effectiveness, SM can cause …

An elusive target: inhibitors of JC polyomavirus infection and their development as therapeutics for the treatment of progressive multifocal leukoencephalopathy

J Kaiserman, BA O'Hara, SA Haley… - International Journal of …, 2023 - mdpi.com
Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease caused
by infection with JC Polyomavirus (JCPyV). Despite the identification of the disease and …

Antineoplastic indole-containing compounds with potential VEGFR inhibitory properties

DR Aboshouk, MA Youssef, MS Bekheit, AR Hamed… - RSC …, 2024 - pubs.rsc.org
Cancer is one of the most significant health challenges worldwide. Various techniques, tools
and therapeutics/materials have been developed in the last few decades for the treatment of …