Naringenin is an important phytochemical which belongs to the flavanone group of
polyphenols, and is found mainly in citrus fruits like grapefruits and others such as tomatoes …

The prevalence of liver cancer is constantly rising, with increasing incidence and mortality in
Europe and the USA in recent decades. Among the different subtypes of liver cancers …

Introduction P53 represents a key player in apoptosis-induction in cancers including
colorectal cancer (CRC) that ranks third worldwide in cancer prevalence as well as mortality …

Cancer stem cells (CSCs) as a small subpopulation in tumor bulk are believed to initiate
tumor formation and are responsible for the resistance to cancer therapy. The proliferation …

Cost-efficacy of currently applied treatments is an issue in overall cancer management
challenging healthcare and causing tremendous economic burden to societies around the …

Despite tremendous medical treatment successes, colorectal cancer (CRC) remains a
leading cause of cancer deaths worldwide. Chemotherapy as monotherapy can lead to …

As an important part of complementary and alternative medicine, traditional Chinese
medicine (TCM) has been applied to treat a host of diseases for centuries. Over the years …

Frequent development of resistance to chemotherapeutic agents such as 5-flourouracil (5-
FU) complicates the treatment of advanced colorectal cancer (CRC). Resveratrol is able to …

Abstract Background Cancer stem cells (CSCs) are strongly associated with high
tumourigenicity, chemotherapy or radiotherapy resistance, and metastasis and recurrence …

Increasing evidence indicate that cancer stem cells (CSCs) are the key driver of tumor
initiation and recurrence. The cellular and soluble components of the tumor …