Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention

Z Khatoon, CD McTiernan, EJ Suuronen, TF Mah… - Heliyon, 2018 - cell.com
In living organisms, biofilms are defined as complex communities of bacteria residing within
an exopolysaccharide matrix that adheres to a surface. In the clinic, they are typically the …

Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus

TJ Foster, JA Geoghegan, VK Ganesh… - Nature reviews …, 2014 - nature.com
Staphylococcus aureus is an important opportunistic pathogen and persistently colonizes
about 20% of the human population. Its surface is' decorated'with proteins that are covalently …

The staphylococcal biofilm: adhesins, regulation, and host response

AE Paharik, AR Horswill - Virulence mechanisms of bacterial …, 2016 - Wiley Online Library
The Staphylococcus genus includes a diverse group of commensals that colonize mammals
on the skin or mucous membranes. Some of the best‐known members of this genus, such as …

[HTML][HTML] Iron in infection and immunity

JE Cassat, EP Skaar - Cell host & microbe, 2013 - cell.com
Iron is an essential nutrient for both humans and pathogenic microbes. Because of its ability
to exist in one of two oxidation states, iron is an ideal redox catalyst for diverse cellular …

Leukocidins: staphylococcal bi-component pore-forming toxins find their receptors

AN Spaan, JAG van Strijp, VJ Torres - Nature Reviews Microbiology, 2017 - nature.com
Staphylococcus aureus is a major bacterial pathogen that causes disease worldwide. The
emergence of strains that are resistant to commonly used antibiotics and the failure of …

Beyond iron: non-classical biological functions of bacterial siderophores

TC Johnstone, EM Nolan - Dalton Transactions, 2015 - pubs.rsc.org
Bacteria secrete small molecules known as siderophores to acquire iron from their
surroundings. For over 60 years, investigations into the bioinorganic chemistry of these …

Staphylococcus aureus pathogenesis in diverse host environments

D Balasubramanian, L Harper, B Shopsin… - Pathogens and …, 2017 - academic.oup.com
Staphylococcus aureus is an eminent human pathogen that can colonize the human host
and cause severe life-threatening illnesses. This bacterium can reside in and infect a wide …

Prokaryotic heme biosynthesis: multiple pathways to a common essential product

HA Dailey, TA Dailey, S Gerdes, D Jahn… - Microbiology and …, 2017 - Am Soc Microbiol
The advent of heme during evolution allowed organisms possessing this compound to
safely and efficiently carry out a variety of chemical reactions that otherwise were difficult or …

The biogeography of polymicrobial infection

A Stacy, L McNally, SE Darch, SP Brown… - Nature Reviews …, 2016 - nature.com
Microbial communities are spatially organized in both the environment and the human body.
Although patterns exhibited by these communities are described by microbial biogeography …

Microbial siderophores: a mini review

R Saha, N Saha, RS Donofrio… - Journal of basic …, 2013 - Wiley Online Library
Iron is one of the major limiting factors and essential nutrients of microbial life. Since in
nature it is not readily available in the preferred form, microorganisms produce small high …