Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …
oncology treatments, emerges in the current management of cancer. A growing number of …
Polymeric nanoparticle-based nanovaccines for cancer immunotherapy
Therapeutic cancer vaccines, which are designed to amplify tumor-specific T cell responses,
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …
Engineering nanosystems to overcome barriers to cancer diagnosis and treatment
Over the past two decades, multidisciplinary investigations into the development of
nanoparticles for medical applications have continually increased. However, nanoparticles …
nanoparticles for medical applications have continually increased. However, nanoparticles …
Transforming nuclear medicine with nanoradiopharmaceuticals
I Roy, S Krishnan, AV Kabashin, IN Zavestovskaya… - ACS …, 2022 - ACS Publications
Nuclear medicine is expected to make major advances in cancer diagnosis and therapy;
tumor-targeted radiopharmaceuticals preferentially eradicate tumors while causing minimal …
tumor-targeted radiopharmaceuticals preferentially eradicate tumors while causing minimal …
[HTML][HTML] Advances in nanomaterials for the diagnosis and treatment of head and neck cancers: A review
C Yu, L Li, S Wang, Y Xu, L Wang, Y Huang, A Hieawy… - Bioactive Materials, 2023 - Elsevier
Nanomaterials (NMs) have increasingly been used for the diagnosis and treatment of head
and neck cancers (HNCs) over the past decade. HNCs can easily infiltrate surrounding …
and neck cancers (HNCs) over the past decade. HNCs can easily infiltrate surrounding …
Prospects of nanoparticle-based radioenhancement for radiotherapy
LRH Gerken, ME Gerdes, M Pruschy… - Materials horizons, 2023 - pubs.rsc.org
Radiotherapy is a key pillar of solid cancer treatment. Despite high level of conformal dose
deposition, radiotherapy is limited due to co-irradiation of organs-at risk and subsequent …
deposition, radiotherapy is limited due to co-irradiation of organs-at risk and subsequent …
Combining a nanoparticle-mediated immunoradiotherapy with dual blockade of LAG3 and TIGIT improves the treatment efficacy in anti-PD1 resistant lung cancer
Y Hu, S Paris, G Bertolet, HB Barsoumian, K He… - Journal of …, 2022 - Springer
Background While improvements in immunoradiotherapy have significantly improved
outcomes for cancer patients, this treatment approach has nevertheless proven ineffective at …
outcomes for cancer patients, this treatment approach has nevertheless proven ineffective at …
NBTXR3 radiotherapy-activated functionalized hafnium oxide nanoparticles show efficient antitumor effects across a large panel of human cancer models
P Zhang, J Marill, A Darmon… - International Journal …, 2021 - Taylor & Francis
Purpose The side effects of radiotherapy induced on healthy tissue limit its use. To
overcome this issue and fully exploit the potential of radiotherapy to treat cancers, the first-in …
overcome this issue and fully exploit the potential of radiotherapy to treat cancers, the first-in …
Radiation therapy enhanced by NBTXR3 nanoparticles overcomes anti-PD1 resistance and evokes abscopal effects
Purpose Radiation combined with PD1 blockade offers significant treatment benefits in
several tumor types; however, anti-PD1 resistance precludes such benefits in many cases …
several tumor types; however, anti-PD1 resistance precludes such benefits in many cases …
Synthesis and bioapplication of emerging nanomaterials of Hafnium
A significant amount of progress in nanotechnology has been made due to the development
of engineered nanoparticles. The use of metallic nanoparticles for various biomedical …
of engineered nanoparticles. The use of metallic nanoparticles for various biomedical …