Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare myeloid malignancy with no
defined standard of care. BPDCN presents most commonly with skin lesions with or without …

Myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) are
reported in up to 20% patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) …

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy
with historically poor outcomes and no worldwide consensus treatment approach. Unique …

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy
arising from the aberrant transformation of plasmacytoid dendritic cells (pDCs) and involving …

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare skin-tropic hematological
malignancy of uncertain pathogenesis and poor prognosis. We examined 118 BPDCN …

Overall, biologists and pathologists need to be alert to the diagnosis of BPDCN, and they
should learn to recognize its characteristics. Because it is rare and depends on recognition …

Cancer stem cells (CSCs) are self-renewing multipotent cells that play a vital role in the
development of cancer drug resistance conditions. Various therapies like conventional …

Rationale: Blastic plasmacytoid dendritic cell neoplasm (BPDCN), derived from precursors
of plasmacytoid dendritic cells, is a rare and aggressive malignancy with frequent cutaneous …

Summary Interferon regulatory factor 8 (IRF8) is a member of the IRF family that is specific to
the hematopoietic cell and is involved in regulating the development of human monocytic …