Current Development of Thiazole-Containing Compounds as Potential Antibacterials against Methicillin-Resistant Staphylococcus aureus

H Liu, T Xu, Z Xue, M Huang, T Wang… - ACS Infectious …, 2024 - ACS Publications
The emergence of multi-drug-resistant bacteria is threatening to human health and life
around the world. In particular, methicillin-resistant Staphylococcus aureus (MRSA) causes …

Single continuous near-infrared laser-triggered photodynamic and photothermal ablation of antibiotic-resistant bacteria using effective targeted copper sulfide …

X Dai, Y Zhao, Y Yu, X Chen, X Wei… - ACS applied materials …, 2017 - ACS Publications
The emergence of antibiotic-resistant bacterial strains has made conventional antibiotic
therapies less efficient. The development of a novel nanoantibiotic approach for efficiently …

Discovery and Characterization of Potent Thiazoles versus Methicillin- and Vancomycin-Resistant Staphylococcus aureus

H Mohammad, AS Mayhoub, A Ghafoor… - Journal of medicinal …, 2014 - ACS Publications
Methicillin-and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA) infections
are growing global health concerns. Structure–activity relationships of phenylthiazoles as a …

Recent Advances in the Synthesis of Thiazole Ring: Mini Review

IG Shahin, KO Mohamed, AT Taher… - Mini-Reviews in …, 2023 - ingentaconnect.com
The thiazole scaffold is an essential structural foundation in a plethora of pharmaceutical
products having an extensive array of biological activities. Consequently, its synthesis has …

Synthesis and biological screening of 2′-aryl/benzyl-2-aryl-4-methyl-4′, 5-bithiazolyls as possible anti-tubercular and antimicrobial agents

YK Abhale, AV Sasane, AP Chavan… - European Journal of …, 2015 - Elsevier
Abstract A series of 2′-aryl/benzyl-2-aryl-4-methyl-4′, 5-bithiazolyl derivatives, 25–64
were synthesized and evaluated for inhibitory activity against Mycobacterium smegmatis MC …

Synthesis and biological evaluation of new 2-aryl-4-((4-aryl-1H-1,2,3-triazol-1-yl)methyl)thiazole derivatives

V Shinde, P Mahulikar, PC Mhaske, L Nawale… - Research on Chemical …, 2018 - Springer
Abstract A series of 2-aryl-4-((4-aryl-1 H-1, 2, 3-triazol-1-yl) methyl) thiazole derivatives (8a–
p) have been synthesized. The structure of the newly synthesized compounds was …

Fused Heterocycles: Synthesis and Antitubercular Activity of Novel 6‐Substituted‐2‐(4‐methyl‐2‐substituted phenylthiazol‐5‐yl)H‐imidazo[1,2‐a]pyridine

YK Abhale, KK Deshmukh, AV Sasane… - Journal of …, 2016 - Wiley Online Library
A series of 6‐substituted‐2‐(4‐methyl‐2‐substituted phenylthiazol‐5‐yl) H‐imidazo [1, 2‐a]
pyridine derivatives 4a, 4b, 4c, 4d, 4e, 4f, 4g, 4h, 4i, 4j, 4k, 4l is described. The antitubercular …

Synthesis, antimycobacterial screening and molecular docking studies of 4-aryl-4′-methyl-2′-aryl-2, 5′-bisthiazole derivatives

YK Abhale, AD Shinde, KK Deshmukh… - Medicinal Chemistry …, 2017 - Springer
Abstract A series of 4-aryl-4′-methyl-2′-aryl-2, 5′-bisthiazole derivatives (5a–o) were
synthesized and screened for inhibitory activity against Mycobacterium tuberculosis H37Ra …

Synthesis and antimicrobial Evaluation of Novel 2'-aryl-4-aryl-2, 4'-Bisthiazole and 2'-aryl-4-Pyridyl-2, 4'-Bisthiazole Derivatives as Potential Antibacterial Agents

J Nalawade, A Shinde, YK Abhale… - Polycyclic Aromatic …, 2024 - Taylor & Francis
In continuation of our research work to explore bisthiazole derivatives as potential
antimicrobial agents, herein we reported the synthesis of a series of novel 2'-aryl-4-aryl-2, 4' …

The Anti-MRSA Activity of Phenylthiazoles: A Comprehensive Review

IG Shahin, KO Mohamed, AT Taher… - Current …, 2022 - ingentaconnect.com
Antimicrobial resistance is an aggravating global issue therefore it has been under
extensive research in an attempt to reduce the number of antibiotics that are constantly …