Lipoprotein (a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

F Kronenberg, S Mora, ESG Stroes… - European heart …, 2022 - academic.oup.com
Abstract This 2022 European Atherosclerosis Society lipoprotein (a)[Lp (a)] consensus
statement updates evidence for the role of Lp (a) in atherosclerotic cardiovascular disease …

Heart disease and stroke statistics—2023 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2023 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association

SS Martin, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

[HTML][HTML] Using genetic association data to guide drug discovery and development: review of methods and applications

S Burgess, AM Mason, AJ Grant, EAW Slob… - The American Journal of …, 2023 - cell.com
Evidence on the validity of drug targets from randomized trials is reliable but typically
expensive and slow to obtain. In contrast, evidence from conventional observational …

Pathogenesis and management of abdominal aortic aneurysm

J Golledge, S Thanigaimani, JT Powell… - European Heart …, 2023 - academic.oup.com
Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …

Established and emerging lipid-lowering drugs for primary and secondary cardiovascular prevention

DT Michaeli, JC Michaeli, S Albers, T Boch… - American Journal of …, 2023 - Springer
Despite treatment with statins, patients with elevated low-density lipoprotein cholesterol
(LDL-C) and triglycerides remain at increased risk for adverse cardiovascular events …

Lipoprotein (a): Knowns, unknowns and uncertainties

M Ruscica, CR Sirtori, A Corsini, GF Watts… - Pharmacological …, 2021 - Elsevier
Over the last 10 years, there have been advances on several aspects of lipoprotein (a)
which are reviewed in the present article. Since the standard immunoassays for measuring …

Lipoprotein (a) and risks of peripheral artery disease, abdominal aortic aneurysm, and major adverse limb events

PE Thomas, S Vedel-Krogh, SF Nielsen… - Journal of the American …, 2023 - jacc.org
Abstract Background Lp (a)(lipoprotein [a])-lowering therapy to reduce cardiovascular
disease is under investigation in phase 3 clinical trials. High Lp (a) may be implicated in …

[HTML][HTML] Association between Lipoprotein (a) and risk of atrial fibrillation: A Systematic Review and Meta-analysis of Mendelian Randomization Studies

S Singh, DP Baars, R Desai, D Singh… - Current problems in …, 2024 - Elsevier
Abstract Background and Aims Lipoprotein (a)(Lp [a]) is an established risk factor for
atherosclerotic cardiovascular disease (ASCVD). However, data on association of Lp (a) …

Circulating lipoprotein (a) levels and health outcomes: Phenome-wide Mendelian randomization and disease-trajectory analyses

SC Larsson, L Wang, X Li, F Jiang, X Chen… - Metabolism, 2022 - Elsevier
Abstract Background Lipoprotein (a)[Lp (a)] is a risk factor for atherosclerotic and valvular
diseases, but its possible role in other diseases has not yet been established. We conducted …