From therapeutic drug monitoring to model‐informed precision dosing for antibiotics
Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have
evolved as important tools to inform rational dosing of antibiotics in individual patients with …
evolved as important tools to inform rational dosing of antibiotics in individual patients with …
Population pharmacokinetics and Bayesian dose adjustment to advance TDM of anti-TB drugs
MGG Sturkenboom, AG Märtson, EM Svensson… - Clinical …, 2021 - Springer
Tuberculosis (TB) is still the number one cause of death due to an infectious disease.
Pharmacokinetics and pharmacodynamics of anti-TB drugs are key in the optimization of TB …
Pharmacokinetics and pharmacodynamics of anti-TB drugs are key in the optimization of TB …
[图书][B] WHO operational handbook on tuberculosis. Module 5: management of tuberculosis in children and adolescents
World Health Organization - 2022 - books.google.com
The aim of this operational handbook is to provide practical guidance on the implementation
of the World Health Organization (WHO) policy recommendations on the prevention and …
of the World Health Organization (WHO) policy recommendations on the prevention and …
A review of population pharmacokinetic analyses of linezolid
E Bandín-Vilar, L García-Quintanilla… - Clinical …, 2022 - Springer
In recent years, many studies on population pharmacokinetics of linezolid have been
conducted. This comprehensive review aimed to summarize population pharmacokinetic …
conducted. This comprehensive review aimed to summarize population pharmacokinetic …
Tuberculous meningitis in children: reducing the burden of death and disability
Tuberculous meningitis disproportionately affects young children. As the most devastating
form of tuberculosis, it is associated with unacceptably high rates of mortality and morbidity …
form of tuberculosis, it is associated with unacceptably high rates of mortality and morbidity …
QT interval prolongation with one or more QT-prolonging agents used as part of a multidrug regimen for rifampicin-resistant tuberculosis treatment: findings from two …
AM Ali, KK Radtke, AC Hesseling… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Rifampicin-resistant tuberculosis (RR-TB) involves treatment with many drugs that can
prolong the QT interval; this risk may increase when multiple QT-prolonging drugs are used …
prolong the QT interval; this risk may increase when multiple QT-prolonging drugs are used …
Population pharmacokinetics of linezolid in tuberculosis patients: dosing regimen simulation and target attainment analysis
The prolonged treatment duration for multidrug-resistant tuberculosis (MDR-TB) makes
linezolid dosing difficult because of adverse effects associated with long-term use. We …
linezolid dosing difficult because of adverse effects associated with long-term use. We …
Pharmacokinetics of antiretroviral and tuberculosis drugs in children with HIV/TB co-infection: a systematic review
TG Jacobs, EM Svensson, V Musiime… - Journal of …, 2020 - academic.oup.com
Introduction Management of concomitant use of ART and TB drugs is difficult because of the
many drug–drug interactions (DDIs) between the medications. This systematic review …
many drug–drug interactions (DDIs) between the medications. This systematic review …
Treatment of rifampicin-resistant tuberculosis disease and infection in children: key updates, challenges and opportunities
Children affected by rifampicin-resistant tuberculosis (RR-TB; TB resistant to at least
rifampicin) are a neglected group. Each year an estimated 25,000–30,000 children develop …
rifampicin) are a neglected group. Each year an estimated 25,000–30,000 children develop …
Multidrug-resistant tuberculosis infection and disease in children: a review of new and repurposed drugs
J Huynh, BJ Marais - Therapeutic advances in infectious …, 2019 - journals.sagepub.com
The World Health Organization estimates that 10 million new cases of tuberculosis (TB)
occurred worldwide in 2017, of which 600,000 were rifampicin or multidrug-resistant …
occurred worldwide in 2017, of which 600,000 were rifampicin or multidrug-resistant …