α-Defensins induce a post-translational modification of low density lipoprotein (LDL) that promotes atherosclerosis at normal levels of plasma cholesterol

R Abu-Fanne, E Maraga, I Abd-Elrahman… - Journal of Biological …, 2016 - ASBMB
Approximately one-half of the patients who develop clinical atherosclerosis have normal or
only modest elevations in plasma lipids, indicating that additional mechanisms contribute to …

Sarcoplasmic/endoplasmic reticulum Ca2+ ATPase C674 promotes ischemia-and hypoxia-induced angiogenesis via coordinated endothelial cell and macrophage …

Y Mei, MD Thompson, Y Shiraishi, RA Cohen… - Journal of molecular and …, 2014 - Elsevier
Ischemia is a complex phenomenon modulated by the concerted action of several cell types.
We have identified that sarcoplasmic/endoplasmic reticulum Ca 2+ ATPase 2 (SERCA 2) …

Attenuation of obesity-induced insulin resistance in mice with heterozygous deletion of ROCK2

H Soliman, JN Varela, V Nyamandi… - International journal of …, 2016 - nature.com
Methods: Male ROCK2+/− mice and their wild-type (WT) littermate controls were fed normal
chow or a high fat diet (HFD) for 18 weeks. Glucose and insulin tolerance tests were …

Regulation of oxidized LDL-induced proliferation and migration in human vascular smooth muscle cells by a novel circ_0007478/miR-638/ROCK2 ceRNA network

Z Guan, R Lu, Y Sun, X Wang, C Yu… - Vascular …, 2023 - journals.sagepub.com
Background: Circular RNAs (circRNAs) have been implicated in the pathogenesis of
atherosclerosis (AS) and the migration and proliferation of vascular smooth muscle cells …

Tribbles homolog 1 enhances cholesterol efflux from oxidized low-density lipoprotein-loaded THP-1 macrophages

Y Fu, Y Zhao, B Huang - Experimental and therapeutic …, 2017 - spandidos-publications.com
Macrophage foam cell formation plays a pivotal role in the pathogenesis of atherosclerosis.
The protein Tribbles homolog 1 (Trib1), a member of the Tribbles protein family, functions as …

Effects and mechanism of moderate aerobic exercise on impaired fasting glucose improvement

H Liao, S Zhong, P Li, W Chen, C Cheng… - Lipids in health and …, 2015 - Springer
Background Exercise is beneficial for blood glucose metabolism. However, whether
moderate aerobic exercise could improve impaired fasting glucose is unknown. And the …

Increased activation of the Rho-A/Rho-kinase pathway in the renal vascular system is responsible for the enhanced reactivity to exogenous vasopressin in …

KL Guarido, RPM Gonçalves, AG Júnior… - Critical Care …, 2014 - journals.lww.com
Objective: We evaluated the role of the renal vascular system and the Rho-A/Rho-kinase
pathway in the maintenance of the pressor effects of vasopressin in endotoxemic rats …

[PDF][PDF] Association of moderate aerobic exercise and rho-associated kinase 2 concentration in subjects with dyslipidemia

H Bai, J Sun, G Du, F Jiao - Archives of Medical Science, 2017 - termedia.pl
Results: At baseline, dyslipidemia in both groups was characterized by increased serum
levels of total cholesterol and low density lipoprotein cholesterol (LDL-C). Serum high …

Molecular Action of Herbal Medicine in Physiology of Erection and its Dysfunction

DM Rizal, N Septiyorini - BIO Web of Conferences, 2022 - bio-conferences.org
Erection is a physiological process that involves vascular, hormonal, and nervous factors.
Erectile dysfunction is one of the male sexual problems that occur globally and is reported to …

[引用][C] RNA 干扰人血凝素样氧化型低密度脂蛋白受体表达对内皮细胞骨架损伤的影响

刘洪光, 屈宝泽, 陶贵周, 黄建华 - 中华老年心脑血管病杂志, 2015