A brief review of cardiovascular diseases, associated risk factors and current treatment regimes
Cardiovascular diseases (CVDs) are the leading cause of premature death and disability in
humans and their incidence is on the rise globally. Given their substantial contribution …
humans and their incidence is on the rise globally. Given their substantial contribution …
[HTML][HTML] Anticoagulation drug therapy: a review
K Harter, M Levine, SO Henderson - Western Journal of …, 2015 - ncbi.nlm.nih.gov
Historically, most patients who required parenteral anticoagulation received heparin,
whereas those patients requiring oral anticoagulation received warfarin. Due to the narrow …
whereas those patients requiring oral anticoagulation received warfarin. Due to the narrow …
[HTML][HTML] The suboptimal fibrinolytic response in COVID‐19 is dictated by high PAI‐1
CS Whyte, M Simpson, GB Morrow, CA Wallace… - Journal of Thrombosis …, 2022 - Elsevier
Background Severe COVID‐19 disease is associated with thrombotic complications and
extensive fibrin deposition. This study investigates whether the hemostatic complications in …
extensive fibrin deposition. This study investigates whether the hemostatic complications in …
[HTML][HTML] Tenecteplase vs. alteplase for acute ischemic stroke: a systematic review
N Potla, L Ganti - International journal of emergency medicine, 2022 - Springer
Introduction Thrombolysis for acute ischemic stroke (AIS) with alteplase is the currently
approved therapy for patients who present within 4.5 h of symptom onset and meet criteria …
approved therapy for patients who present within 4.5 h of symptom onset and meet criteria …
[HTML][HTML] Infecção e óbitos de profissionais da saúde por COVID-19: revisão sistemática
Objetivo Identificar as evidências quanto à infecção pelo SARS-CoV-2 e óbitos dos
profissionais de saúde e fatores de risco relacionados. Métodos Realizou-se uma revisão …
profissionais de saúde e fatores de risco relacionados. Métodos Realizou-se uma revisão …
[HTML][HTML] Review of stroke thrombolytics
The cornerstone of acute ischemic stroke treatment relies on rapid clearance of an offending
thrombus in the cerebrovascular system. There are various drugs and different methods of …
thrombus in the cerebrovascular system. There are various drugs and different methods of …
Delivery of drugs bound to erythrocytes: new avenues for an old intravascular carrier
CH Villa, DC Pan, S Zaitsev, DB Cines… - Therapeutic …, 2015 - Future Science
For several decades, researchers have used erythrocytes for drug delivery of a wide variety
of therapeutics in order to improve their pharmacokinetics, biodistribution, controlled release …
of therapeutics in order to improve their pharmacokinetics, biodistribution, controlled release …
Co-production of microbial polyhydroxyalkanoates with other chemicals
T Li, D Elhadi, GQ Chen - Metabolic engineering, 2017 - Elsevier
Engineering microorganisms capable of simultaneously accumulating multiple products are
economically attractive for biotechnology. Polyhydroxyalkanoates (PHA) or microbial …
economically attractive for biotechnology. Polyhydroxyalkanoates (PHA) or microbial …
Advanced drug delivery systems for antithrombotic agents
CF Greineder, MD Howard… - Blood, The Journal …, 2013 - ashpublications.org
Despite continued achievements in antithrombotic pharmacotherapy, difficulties remain in
managing patients at high risk for both thrombosis and hemorrhage. Utility of antithrombotic …
managing patients at high risk for both thrombosis and hemorrhage. Utility of antithrombotic …
[HTML][HTML] Comparison of three Escherichia coli strains in recombinant production of reteplase
M Fathi-Roudsari, A Akhavian-Tehrani… - Avicenna journal of …, 2016 - ncbi.nlm.nih.gov
Background: Escherichia coli (E. coli) is the most extensively used host for the production of
recombinant proteins. However, most of the eukaryotic proteins are typically obtained as …
recombinant proteins. However, most of the eukaryotic proteins are typically obtained as …