A brief review of cardiovascular diseases, associated risk factors and current treatment regimes

GD Flora, MK Nayak - Current pharmaceutical design, 2019 - ingentaconnect.com
Cardiovascular diseases (CVDs) are the leading cause of premature death and disability in
humans and their incidence is on the rise globally. Given their substantial contribution …

[HTML][HTML] Anticoagulation drug therapy: a review

K Harter, M Levine, SO Henderson - Western Journal of …, 2015 - ncbi.nlm.nih.gov
Historically, most patients who required parenteral anticoagulation received heparin,
whereas those patients requiring oral anticoagulation received warfarin. Due to the narrow …

[HTML][HTML] The suboptimal fibrinolytic response in COVID‐19 is dictated by high PAI‐1

CS Whyte, M Simpson, GB Morrow, CA Wallace… - Journal of Thrombosis …, 2022 - Elsevier
Background Severe COVID‐19 disease is associated with thrombotic complications and
extensive fibrin deposition. This study investigates whether the hemostatic complications in …

[HTML][HTML] Tenecteplase vs. alteplase for acute ischemic stroke: a systematic review

N Potla, L Ganti - International journal of emergency medicine, 2022 - Springer
Introduction Thrombolysis for acute ischemic stroke (AIS) with alteplase is the currently
approved therapy for patients who present within 4.5 h of symptom onset and meet criteria …

[HTML][HTML] Infecção e óbitos de profissionais da saúde por COVID-19: revisão sistemática

G Sant'Ana, AM Imoto, FF Amorim… - Acta Paulista de …, 2020 - SciELO Brasil
Objetivo Identificar as evidências quanto à infecção pelo SARS-CoV-2 e óbitos dos
profissionais de saúde e fatores de risco relacionados. Métodos Realizou-se uma revisão …

[HTML][HTML] Review of stroke thrombolytics

A Bivard, L Lin, MW Parsonsb - Journal of stroke, 2013 - ncbi.nlm.nih.gov
The cornerstone of acute ischemic stroke treatment relies on rapid clearance of an offending
thrombus in the cerebrovascular system. There are various drugs and different methods of …

Delivery of drugs bound to erythrocytes: new avenues for an old intravascular carrier

CH Villa, DC Pan, S Zaitsev, DB Cines… - Therapeutic …, 2015 - Future Science
For several decades, researchers have used erythrocytes for drug delivery of a wide variety
of therapeutics in order to improve their pharmacokinetics, biodistribution, controlled release …

Co-production of microbial polyhydroxyalkanoates with other chemicals

T Li, D Elhadi, GQ Chen - Metabolic engineering, 2017 - Elsevier
Engineering microorganisms capable of simultaneously accumulating multiple products are
economically attractive for biotechnology. Polyhydroxyalkanoates (PHA) or microbial …

Advanced drug delivery systems for antithrombotic agents

CF Greineder, MD Howard… - Blood, The Journal …, 2013 - ashpublications.org
Despite continued achievements in antithrombotic pharmacotherapy, difficulties remain in
managing patients at high risk for both thrombosis and hemorrhage. Utility of antithrombotic …

[HTML][HTML] Comparison of three Escherichia coli strains in recombinant production of reteplase

M Fathi-Roudsari, A Akhavian-Tehrani… - Avicenna journal of …, 2016 - ncbi.nlm.nih.gov
Background: Escherichia coli (E. coli) is the most extensively used host for the production of
recombinant proteins. However, most of the eukaryotic proteins are typically obtained as …