Novel diagnostic biomarkers in colorectal cancer

AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

Circulating microRNAs as biomarkers in cancer diagnosis

MMH Sohel - Life sciences, 2020 - Elsevier
MicroRNAs (miRNAs) are a group of tiny molecules of 18–22 nucleotide long noncoding
RNA that regulate the post-transcriptional gene expression through translational inhibition …

The role of MiRNA in cancer: pathogenesis, diagnosis, and treatment

E Uzuner, GT Ulu, SB Gürler, Y Baran - miRNomics: MicroRNA Biology …, 2022 - Springer
Cancer is also determined by the alterations of oncogenes and tumor suppressor genes.
These gene expressions can be regulated by microRNAs (miRNA). At this point, researchers …

[HTML][HTML] Biomarkers for detecting colorectal cancer non-invasively: DNA, RNA or proteins?

A Loktionov - World journal of gastrointestinal oncology, 2020 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a global problem affecting millions of people worldwide. This
disease is unique because of its slow progress that makes it preventable and often curable …

Advances in tests for colorectal cancer screening and diagnosis

SCH Chan, JQ Liang - Expert review of molecular diagnostics, 2022 - Taylor & Francis
Introduction Colorectal cancer (CRC) is the second leading cause of cancer-related deaths
globally. Nonetheless, with early detection of CRC or its precancerous lesions, mortality, and …

[HTML][HTML] Omics technologies for improved diagnosis and treatment of colorectal cancer: Technical advancement and major perspectives

N Dalal, R Jalandra, M Sharma, H Prakash… - Biomedicine & …, 2020 - Elsevier
Colorectal cancer (CRC) ranks third among the most commonly occurring cancers
worldwide, and it causes half a million deaths annually. Alongside mechanistic study for …

Multi-omics approaches in colorectal cancer screening and diagnosis, recent updates and future perspectives

I Ullah, L Yang, FT Yin, Y Sun, XH Li, J Li, XJ Wang - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is one of the most prevalent cancers worldwide.
Due to the absence of specific early symptoms, most of CRC patients are often diagnosed at …

[HTML][HTML] miR-545 promotes colorectal cancer by inhibiting transferring in the non-normal ferroptosis signaling

S Zheng, L Hu, Q Song, Y Shan, G Yin, H Zhu… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
In this study, we examined whether and how miR-545 modulates ferroptosis in colorectal
cancer (CRC). HT-29 and HCT-116 human CRC cell viability was examined using a CCK-8 …

Neurons can upregulate Cav-1 to increase intake of endothelial cells-derived extracellular vesicles that attenuate apoptosis via miR-1290

KY Yue, PR Zhang, MH Zheng, XL Cao, Y Cao… - Cell death & …, 2019 - nature.com
Extracellular vesicles (EVs) including exosomes can serve as mediators of cell–cell
communication under physiological and pathological conditions. However, cargo molecules …

Fecal microRNAs as innovative biomarkers of intestinal diseases and effective players in host-microbiome interactions

M Sarshar, D Scribano, C Ambrosi, AT Palamara… - Cancers, 2020 - mdpi.com
Over the past decade, short non-coding microRNAs (miRNAs), including circulating and
fecal miRNAs have emerged as important modulators of various cellular processes by …