Quantitative systems pharmacology and machine learning: a match made in heaven or hell?
As pharmaceutical development moves from early-stage in vitro experimentation to later in
vivo and subsequent clinical trials, data and knowledge are acquired across multiple time …
vivo and subsequent clinical trials, data and knowledge are acquired across multiple time …
Utility of Minimal Physiologically Based Pharmacokinetic Models for Assessing Fractional Distribution, Oral Absorption, and Series-Compartment Models of Hepatic …
X Li, WJ Jusko - Drug Metabolism and Disposition, 2023 - ASPET
Minimal physiologically based pharmacokinetic (mPBPK) models are physiologically
relevant, require less information than full PBPK models, and offer flexibility in …
relevant, require less information than full PBPK models, and offer flexibility in …