The frequency and distribution of B and T lymphocyte subsets have been determined in
many body tissues and fluids by preparing cell suspensions and tissue sections from …

Lymphocytes continuously enter and exit lymphoid and non-lymphoid organs using the
blood as a traffic route (reviewed in Refs 1, 2). The determination of lymphocyte subsets in …

Cerebrospinal fluid (CSF) from healthy individuals contains between 1,000 and 3,000
leukocytes per ml. Little is known about trafficking patterns of leukocytes between the …

The cerebrospinal fluid (CSF) of multiple sclerosis (MS) patients is characterized by
increased concentrations of immunoglobulin (Ig), which on electrophoretic analysis shows …

The role of various adhesion molecules in lymphocyte homing to the brain and in
inflammatory autoimmune disease of the central nervous system (CNS) was examined in …

Tumor necrosis factor (TNF) activity was inhibited during the development of actively‐
induced, chronic relapsing experimental allergic encephalomyelitis (CREAE) in Biozzi AB/H …

THE identification of activated? cells in the brain of individuals with multiple sclerosis (MS)
indicates that these cells are critical in the pathogenesis of this disease. In an attempt to …

The integrity of the blood-brain barrier (BBB) in multiple sclerosis (MS) was monitored by
serial gadolinium-(Gd)-DTPA enhanced MRI during and after the treatment of acute relapses …

Mu~ e sderosis (MS) is an inflammatory disease which exclusively affects the white matter of
the central nervous system (CNS). Although there is a localized immune response within the …

Myelin proteins, including myelin basic protein (MBP), proteolipid protein (PLP) and myelin
oligodendrocyte glycoprotein (MOG) are candidate autoantigens in MS. It is not clear …