Oxidative stress and inflammation regulation of sirtuins: New insights into common oral diseases

Z Pan, H Dong, N Huang, J Fang - Frontiers in Physiology, 2022 - frontiersin.org
Sirtuins are a family of nicotinamide adenine dinucleotide (NAD)+-dependent histone
deacetylases, comprising seven members SIRT1-SIRT7. Sirtuins have been extensively …

Sirtuins and their influence on autophagy

MW Baeken - Journal of Cellular Biochemistry, 2023 - Wiley Online Library
Sirtuins and autophagy are well‐characterized agents that can promote longevity and
protect individual organisms from age‐associated diseases like neurodegenerative …

Quercetin promotes in vitro maturation of oocytes from humans and aged mice

Y Cao, H Zhao, Z Wang, C Zhang, Y Bian, X Liu… - Cell Death & …, 2020 - nature.com
Maternal fertility declines irreversibly with aging, and advanced maternal age is mostly
related to impaired oocyte quality. The flavonol compound quercetin is considered to be an …

Host sirtuin 2 as an immunotherapeutic target against tuberculosis

A Bhaskar, S Kumar, MZ Khan, A Singh, VP Dwivedi… - Elife, 2020 - elifesciences.org
Mycobacterium tuberculosis (Mtb) employs plethora of mechanisms to hijack the host
defence machinery for its successful survival, proliferation and persistence. Here, we show …

Impaired placental mitophagy and oxidative stress are associated with dysregulated BNIP3 in preeclampsia

X Zhou, X Zhao, W Zhou, H Qi, H Zhang, T Han… - Scientific Reports, 2021 - nature.com
Preeclampsia (PE) is a severe multisystem pregnancy complication characterized by
gestational hypertension and proteinuria. Bcl-2/adenovirus E1B 19-kDa interacting protein 3 …

Aging and oocyte competence: A molecular cell perspective

AF Ferreira, M Soares… - WIREs Mechanisms …, 2023 - Wiley Online Library
Follicular microenvironment is paramount in the acquisition of oocyte competence, which is
dependent on two interconnected and interdependent processes: nuclear and cytoplasmic …

Fisetin Delays Postovulatory Oocyte Aging by Regulating Oxidative Stress and Mitochondrial Function through Sirt1 Pathway

X Xing, Y Liang, Y Li, Y Zhao, Y Zhang, Z Li, Z Li, Z Wu - Molecules, 2023 - mdpi.com
The quality of oocytes determines the development potential of an embryo and is dependent
on their timely fertilization after ovulation. Postovulatory oocyte aging is an inevitable factor …

SIRT2 is critical for sheep oocyte maturation through regulating function of surrounding granulosa cells

X Fang, W Xia, S Li, Y Qi, M Liu, Y Yu, H Li, M Li… - International Journal of …, 2022 - mdpi.com
Oocyte in vitro maturation is crucial for in vitro embryo production technology, which
provides oocytes resources for in vitro fertilization and somatic cell nuclear transfer. Previous …

Autophagy is a pro-survival adaptive response to heat shock in bovine cumulus-oocyte complexes

LB Latorraca, WB Feitosa, C Mariano, MT Moura… - Scientific Reports, 2020 - nature.com
Autophagy is a physiological mechanism that can be activated under stress conditions.
However, the role of autophagy during oocyte maturation has been poorly investigated …

SIRT2 inhibition exacerbates p53-mediated ferroptosis in mice following experimental traumatic brain injury

J Gao, Y Li, R Song - Neuroreport, 2021 - journals.lww.com
Objective Ferroptosis plays an important role in traumatic brain injury (TBI). The p53 protein
is a major mediator of ferroptosis. However, the role of p53-mediated ferroptosis in TBI has …