Recent developments in optical detection technologies in lab-on-a-chip devices for biosensing applications

NMM Pires, T Dong, U Hanke, N Hoivik - Sensors, 2014 - mdpi.com
The field of microfluidics has yet to develop practical devices that provide real clinical value.
One of the main reasons for this is the difficulty in realizing low-cost, sensitive, reproducible …

Microfluidic approaches for isolation, detection, and characterization of extracellular vesicles: Current status and future directions

S Gholizadeh, MS Draz, M Zarghooni… - Biosensors and …, 2017 - Elsevier
Extracellular vesicles (EVs) are cell-derived vesicles present in body fluids that play an
essential role in various cellular processes, such as intercellular communication …

Optical sensing systems for microfluidic devices: a review

B Kuswandi, J Huskens, W Verboom - Analytica chimica acta, 2007 - Elsevier
This review deals with the application of optical sensing systems for microfluidic devices. In
the “off-chip approach” macro-scale optical infrastructure is coupled, while the “on-chip …

Recent developments in optical detection methods for microchip separations

S Götz, U Karst - Analytical and Bioanalytical Chemistry, 2007 - Springer
This paper summarizes the features and performances of optical detection systems currently
applied in order to monitor separations on microchip devices. Fluorescence detection, which …

Review of microfluidic approaches for surface-enhanced Raman scattering

Q Zhou, T Kim - Sensors and Actuators B: Chemical, 2016 - Elsevier
The development of lab-on-a-chip (LoC) systems has allowed for the successful
combination of many detection methods with these systems. Surface-enhanced Raman …

Localized flexible integration of high-efficiency surface enhanced Raman scattering (SERS) monitors into microfluidic channels

BB Xu, ZC Ma, L Wang, R Zhang, LG Niu, Z Yang… - Lab on a Chip, 2011 - pubs.rsc.org
We report here a facile approach for flexible integration of high efficiency surface enhanced
Raman scattering (SERS) monitors in a continuous microfluidic channel. In our work …

Recent advances in IEF in capillary tubes and microchips

K Shimura - Electrophoresis, 2009 - Wiley Online Library
The methodological advancements in CIEF in tubes and microchips during the period
between 2002 and early 2008 are reviewed as a continuation of previous review by the …

Recent progress of online sample preconcentration techniques in microchip electrophoresis

K Sueyoshi, F Kitagawa… - Journal of separation …, 2008 - Wiley Online Library
Microchip electrophoresis (MCE) has been advanced remarkably by the applications of
several separation modes and the integration with several chemical operations on a single …

Protein separation under a microfluidic regime

I Rodríguez-Ruiz, V Babenko, S Martínez-Rodríguez… - Analyst, 2018 - pubs.rsc.org
Lab-on-a-Chip (LoC), or micro-Total Analysis Systems (μTAS), is recognized as a powerful
analytical technology with high capabilities, though end-user products for protein purification …

A SERS‐active microfluidic device with tunable surface plasmon resonances

BB Xu, ZC Ma, H Wang, XQ Liu, YL Zhang… - …, 2011 - Wiley Online Library
A surface‐enhanced Raman scattering (SERS)‐active microfluidic device with tunable
surface plasmon resonances is presented here. It is constructed by silver grating substrates …