[HTML][HTML] Human placental development and function

T Cindrova-Davies, AN Sferruzzi-Perri - Seminars in cell & developmental …, 2022 - Elsevier
The placenta is a transient fetal organ that plays a critical role in the health and wellbeing of
both the fetus and its mother. Functionally, the placenta sustains the growth of the fetus as it …

Maternal obesity: new placental paradigms unfolded

C Brombach, W Tong, DA Giussani - Trends in molecular medicine, 2022 - cell.com
The prevalence of maternal obesity is increasing at an alarming rate, and is providing a
major challenge for obstetric practice. Adverse effects on maternal and fetal health are …

Self‐assembled human placental model from trophoblast stem cells in a dynamic organ‐on‐a‐chip system

R Cao, Y Wang, J Liu, L Rong, J Qin - Cell Proliferation, 2023 - Wiley Online Library
The placental barrier plays a key role in protecting the developing fetus from xenobiotics and
exchanging substances between the fetus and mother. However, the trophoblast cell lines …

High energy diet of beef cows during gestation promoted growth performance of calves by improving placental nutrients transport

K Kang, L Zeng, J Ma, L Shi, R Hu, H Zou… - Frontiers in Veterinary …, 2022 - frontiersin.org
The aim of this study was to explore the effects of dietary energy level during gestation on
growth performance and serum parameters in offspring using beef cattle as research …

Placental nutrient transporters and maternal fatty acids in SGA, AGA, and LGA newborns from mothers with and without obesity

JA Garcia-Santillan… - Frontiers in Cell and …, 2022 - frontiersin.org
Adverse environmental factors in early life result in fetal metabolic programming and
increased risk of adult diseases. Birth weight is an indirect marker of the intrauterine …

Bridging the gap: glucose transporters, Alzheimer's, and future therapeutic prospects

M Albaik, D Sheikh Saleh, D Kauther… - Frontiers in Cell and …, 2024 - frontiersin.org
Glucose is the major source of chemical energy for cell functions in living organisms. The
aim of this mini-review is to provide a clearer and simpler picture of the fundamentals of …

[HTML][HTML] Glucose and oxygen in the early intrauterine environment and their role in developmental abnormalities

A Hufnagel, ID Grant, CEM Aiken - Seminars In Cell & Developmental …, 2022 - Elsevier
The early life environment can have profound impacts on the developing conceptus in terms
of both growth and morphogenesis. These impacts can manifest in a variety of ways …

Glucose Regulates Glucose Transport and Metabolism via mTOR Signaling Pathway in Bovine Placental Trophoblast Cells

L Shi, K Kang, Z Wang, J Wang, J Xiao, Q Peng, R Hu… - Animals, 2023 - mdpi.com
Simple Summary During pregnancy, especially the perinatal period, cows are often in a
state of negative energy balance due to the imbalance of glucose metabolism. As the main …

Altered expression of nutrient transporters in syncytiotrophoblast membranes in preeclampsia placentae

N Joshi, A Sahay, A Mane, D Sundrani, K Randhir… - Placenta, 2023 - Elsevier
Introduction Expression of nutrient transporters in the placenta affects fetal growth. This
study reports the protein expression of nutrient transporters in the syncytial membranes …

Inducible knockout of syncytin-a leads to poor placental glucose transport in mice

YN Wang, YX Ye, ZW Guo, ZL Xiong, QS Sun, D Zhou… - Placenta, 2022 - Elsevier
Introduction Cell-cell fusion of cytotrophoblasts into the syncytiotrophoblast layer is a key
process in placental development. Syncytin, an endogenous retroviral envelope protein, is …