Maximizing the information content of experiments in systems biology
Our understanding of most biological systems is in its infancy. Learning their structure and
intricacies is fraught with challenges, and often side-stepped in favour of studying the …
intricacies is fraught with challenges, and often side-stepped in favour of studying the …
Physiology of mycobacteria
Mycobacterium tuberculosis is a prototrophic, metabolically flexible bacterium that has
achieved a spread in the human population that is unmatched by any other bacterial …
achieved a spread in the human population that is unmatched by any other bacterial …
Simultaneous tracking of autophagy and oxidative stress during stroke with an ICT-TBET integrated ratiometric two-photon platform
W Hu, T Qiang, L Chai, T Liang, L Ren, F Cheng… - Chemical …, 2022 - pubs.rsc.org
Over recent years, fluorescent probes exhibiting simultaneous responses to multiple targets
have been developed for in situ, real-time monitoring of cellular metabolism using two …
have been developed for in situ, real-time monitoring of cellular metabolism using two …
Minimal out-of-equilibrium metabolism for synthetic cells: a membrane perspective
E Bailoni, M Partipilo, J Coenradij… - ACS Synthetic …, 2023 - ACS Publications
Life-like systems need to maintain a basal metabolism, which includes importing a variety of
building blocks required for macromolecule synthesis, exporting dead-end products, and …
building blocks required for macromolecule synthesis, exporting dead-end products, and …
Regulation by transcription factors in bacteria: beyond description
E Balleza, LN Lopez-Bojorquez… - FEMS microbiology …, 2008 - academic.oup.com
Transcription is an essential step in gene expression and its understanding has been one of
the major interests in molecular and cellular biology. By precisely tuning gene expression …
the major interests in molecular and cellular biology. By precisely tuning gene expression …
Chinese herbs as alternatives to antibiotics in feed for swine and poultry production: potential and challenges in application
J Gong, F Yin, Y Hou, Y Yin - Canadian Journal of Animal …, 2014 - cdnsciencepub.com
Gong, J., Yin, F., Hou, Y. and Yin, Y. 2014. Chinese herbs as alternatives to antibiotics in
feed for swine and poultry production: Potential and challenges in application. Can. J. Anim …
feed for swine and poultry production: Potential and challenges in application. Can. J. Anim …
Process analytical technology (PAT) for biopharmaceuticals
Process analytical technology (PAT), the regulatory initiative for building in quality to
pharmaceutical manufacturing, has a great potential for improving biopharmaceutical …
pharmaceutical manufacturing, has a great potential for improving biopharmaceutical …
Reductionistic and holistic science
FC Fang, A Casadevall - Infection and immunity, 2011 - Am Soc Microbiol
ABSTRACT A reductionistic approach to science, epitomized by molecular biology, is often
contrasted with the holistic approach of systems biology. However, molecular biology and …
contrasted with the holistic approach of systems biology. However, molecular biology and …
Massive computational acceleration by using neural networks to emulate mechanism-based biological models
For many biological applications, exploration of the massive parametric space of a
mechanism-based model can impose a prohibitive computational demand. To overcome …
mechanism-based model can impose a prohibitive computational demand. To overcome …
Advances in cardiovascular biomarker discovery
Cardiovascular diseases are the leading causes of mortality worldwide. Among them,
hypertension and its pathological complications pose a major risk for the development of …
hypertension and its pathological complications pose a major risk for the development of …