Cranial placodes are focal regions of thickened ectoderm in the head of vertebrate embryos
that give rise to a wide variety of cell types, including elements of the paired sense organs …

Cranial placodes are specialized regions of the ectoderm, which give rise to various sensory
ganglia and contribute to the pituitary gland and sensory organs of the vertebrate head …

To examine the relationship between growth hormone (GH) and insulin-like growth factor 1
(IGF1) in controlling postnatal growth, we performed a comparative analysis of dwarfing …

The pituitary gland has provided unique insight into molecular mechanisms and regulatory
factors controling both differentiation and gene transcription. We identified Tpit, a novel T …

Cranial placodes (which include the adenohypophyseal, olfactory, lens, otic, lateral line,
profundal/trigeminal, and epibranchial placodes) give rise to many sense organs and …

POU domain factors are transcriptional regulators characterized by a highly conserved DNA-
binding domain referred to as the POU domain. The structure of the POU domain has been …

Pituitary gland commitment from oral ectoderm occurs in response to inductive signals from
the neuroepithelium of the ventral diencephalon. Invagination of the oral ectoderm leads to …

Foxl2 is a member of the large family of Forkhead Box (Fox) domain transcription factors. It
emerged during the last 15 years as a key player in ovarian differentiation and oogenesis in …

Formation of the adenohypophysis in mammalian embryos occurs via an invagination of the
oral ectoderm to form Rathke's pouch, which becomes exposed to opposing dorsoventral …

The pituitary gland has the primordial ability to dynamically adapt its cell composition to
changing hormonal needs of the organism throughout life. During the first weeks after birth …