Elevated pro-inflammatory biomarkers and cytokines are associated with morbidity and
mortality in heart failure (HF). Preclinical and clinical studies have shown multiple …

Acute myocardial infarction (AMI) is associated with the induction of a sterile inflammatory
response that leads to further injury. The NACHT, leucine-rich repeat, and pyrin domain …

Despite advances in the treatment of heart failure, prognosis is poor, mortality high and there
remains no cure. Heart failure is associated with reduced cardiac pump function, autonomic …

Abstract Purpose of Review In heart failure, whether it is associated with reduced or
preserved ejection fraction, the immune system is activated and contributes to heart …

Background An exuberant and dysregulated inflammatory response contributes to the
development and progression of cardiovascular diseases (CVDs). Methods This narrative …

Following a myocardial infarction (MI), the immune system helps to repair ischaemic
damage and restore tissue integrity, but excessive inflammation has been implicated in …

Cardiovascular diseases are known as the leading cause of morbidity and mortality
worldwide. As an innate immune signaling complex, inflammasomes can be activated by …

Cardiomyopathies (CMPs) represent a diverse group of heart muscle diseases, grouped into
specific morphological and functional phenotypes. CMPs are associated with mutations in …

Many cytokines are currently under investigation as potential target to improve cardiac
function and outcome in the setting of acute myocardial infarction (MI) or chronic heart failure …

Over time, patients with longstanding pulmonary arterial hypertension (PAH) experience
pressure overload in the right ventricle (RV), leading to reduced contractile force and …