Right ventricular failure (RVF) is the main determinant of mortality in patients with pulmonary
arterial hypertension (PAH). Although the exact pathophysiology underlying RVF remains …

Interleukin 1 (IL-1) family is a group of cytokines with multiple local and systemic effects,
which regulates both innate and adaptive immune responses. Generally, most IL-1 family …

Background Heart failure (HF) is a global leading cause of mortality despite implementation
of guideline directed therapy which warrants a need for novel treatment strategies. Proof-of …

Abstract Purpose of Review Pericarditis is a generally benign disease, although
complications and/or recurrences may occur in up to 30% of cases. New evidence on the …

Pericarditis is a debilitating condition that results from profound inflammation of the
pericardial tissue. Between 10 and 15% of first episodes of acute pericarditis will be followed …

Dilated cardiomyopathy (DCM) is characterized by LV (left ventricular) or biventricular
systolic dysfunction and dilation, not explained by abnormal loading conditions or coronary …

Virus-negative or autoimmune myocarditis (VNM) is an inflammatory disease affecting the
myocardium that may occur as a distinct disease with exclusive cardiac involvement, or in …

Introduction: Sarcoidosis is a multi-organ disease with a wide range of clinical
manifestations and outcomes. A quarter of sarcoidosis patients require long-term treatment …

Interleukin (IL)-1β plays an important role in atherosclerosis pathogenesis. We aimed to
investigate the effect of anakinra, a recombinant human IL-1 receptor antagonist, on the …

The right and left ventricles have traditionally been studied as individual entities.
Furthermore, modifications found in diseased left ventricles are assumed to influence on …