Histone deacetylase 6 (HDAC6) is a peculiar HDAC isoform whose expression and
functional alterations have been correlated with a variety of pathologies such as …

HIV-1 has evolved a plethora of strategies to overcome the cytoskeletal barrier (ie, actin and
intermediate filaments (AFs and IFs) and microtubules (MTs)) to achieve the viral cycle. HIV …

Abstract Histone deacetylase 6 (HDAC6) is associated with multiple neurological disorders
as well as aggressive cancers, making its selective inhibition highly desirable for therapeutic …

HDAC6 plays a central role in the recruitment of protein aggregates for lysosomal
degradation and is a promising target for combination therapy with proteasome inhibitors in …

Abstract Prominin-1 (CD133) is a cholesterol-binding membrane glycoprotein selectively
associated with highly curved and prominent membrane structures. It is widely recognized …

Targeting histone deacetylases (HDACs) and phosphatidylinositol 3‐kinases (PI3Ks) is a
very promising approach for cancer treatment. This manuscript describes the design …

Malformations of cortical development (MCDs) are a group of severe brain malformations
associated with intellectual disability and refractory childhood epilepsy. Human missense …

Among the metal-dependent histone deacetylases, the class IIb isozyme HDAC6 is
remarkable because of its role in the regulation of microtubule dynamics in the cytosol …

Influenza A virus (IAV) is an enveloped virus of the Orthomyxoviridae with a negative-sense
single-stranded RNA genome. During virus cell entry, viral and cellular cues are delivered in …

Multiple myeloma (MM), a cancer of plasma cells, is the second most common
hematological malignancy which is characterized by aberrant plasma cells infiltration in the …