Long‐term repopulating haematopoietic stem cells (LT‐HSCs) have the ability to
reconstitute the entire haematopoietic system following transplantation permanently. Despite …

Unlike mammals, zebrafish are capable to regenerate many of their organs, however, the
response of tissue damage varies across tissues. Understanding the molecular mechanism …

Worrying about potential radiation exposure is a general concern, but no effective pre-
exposure radioprotective countermeasure is generally accepted1. Here, we found a small …

Abstract Background Hematopoietic stem cells (HSCs) from different sources show varied
repopulating capacity, and HSCs lose their stemness after long‐time ex vivo culture. A deep …

Langerhans cell histiocytosis (LCH) is an inflammatory disease characterized by abnormal
dendritic cells (DCs) with hyperactive ERK signaling, called “LCH cells.” Since DCs rely on …

Ribosome heterogeneity has been revealed to exist in different cell types during
development. However, the function and regulatory mechanisms of ribosome heterogeneity …

Programmed cell death is a complex and tightly regulated sequence of events that
determines cell fate during tissue homeostasis, development, and pathogenesis. The small …

Ageing is characterized by physiological decline and increased risk of agerelated diseases.
The mitochondrial prohibitin (PHB) complex, a ringlike structure in the inner mitochondrial …

Undergoing endothelial-to-hematopoietic transition, a small fraction of embryonic aortic
endothelial cells specializes into hemogenic endothelial cells (HECs) and eventually gives …

Expanding hematopoietic stem cells (HSCs) ex vivo has historically been a very challenging
process. In this issue of Cell Stem Cell, Kruta et al.(2021) identify heat shock factor 1 (Hsf1) …