Viruses are intracellular parasitic organisms with infectious potential and are divided into
two categories, namely DNA viruses and RNA viruses, according to their genomic …

Ribosome heterogeneity has been revealed to exist in different cell types during
development. However, the function and regulatory mechanisms of ribosome heterogeneity …

Programmed cell death is a complex and tightly regulated sequence of events that
determines cell fate during tissue homeostasis, development, and pathogenesis. The small …

Ageing is characterized by physiological decline and increased risk of agerelated diseases.
The mitochondrial prohibitin (PHB) complex, a ringlike structure in the inner mitochondrial …

Undergoing endothelial-to-hematopoietic transition, a small fraction of embryonic aortic
endothelial cells specializes into hemogenic endothelial cells (HECs) and eventually gives …

Expanding hematopoietic stem cells (HSCs) ex vivo has historically been a very challenging
process. In this issue of Cell Stem Cell, Kruta et al.(2021) identify heat shock factor 1 (Hsf1) …

Protein synthesis regulation constitutes a key node in directing decisions between
hematopoietic stemness and differentiation. In this issue of Cell Stem Cell, Lv et al.(2021) …

A previous study using Thermostable Group II Intron Reverse Transcriptase sequencing
(TGIRT-seq) found human plasma contains short (≤ 300 nt) structured full-length excised …

Mechanistic studies of how protein ubiquitylation regulates the cell cycle, in particular during
mitosis, has provided unique insights which have contributed to the emergence of the …

Although important advances have been made in the knowledge of the molecular
mechanisms leading to the development, of head and neck squamous cell carcinoma …