Extracellular vesicles generated by placental tissues ex vivo: A transport system for immune mediators and growth factors

W Fitzgerald, N Gomez‐Lopez, O Erez… - American Journal of …, 2018 - Wiley Online Library
Problem To study the mechanisms of placenta function and the role of extracellular vesicles
(EV s) in pregnancy, it is necessary to develop an ex vivo system that retains placental …

The mediation of the placenta on the association between maternal ambient temperature exposure and birth weight

M Wulayin, Z Zhu, H Wang, X Chen, X Zhang… - Science of The Total …, 2023 - Elsevier
Studies have indicated that exposure to low and high temperatures during pregnancy
negatively affects fetal development. The placenta plays vital functions in fetal development …

DNA methylation abnormalities induced by advanced maternal age in villi prime a high-risk state for spontaneous abortion

M Qin, W Chen, L Hua, Y Meng, J Wang, H Li… - Clinical …, 2023 - Springer
Background Advanced maternal age (AMA) has increased in many high-income countries in
recent decades. AMA is generally associated with a higher risk of various pregnancy …

A Balancing Act: Navigating Hypertensive Disorders of Pregnancy at Very Advanced Maternal Age, from Preconception to Postpartum

M Lopian, L Kashani-Ligumsky, A Many - Journal of Clinical Medicine, 2023 - mdpi.com
The decision to postpone parenting has gained momentum in recent years, a shift driven by
evolving social dynamics and improved access to fertility treatments. Despite their …

Inequalities in birth weight in relation to maternal factors: a population-based study of 3,813,757 live births

A Genowska, R Motkowski, V Strukcinskaite… - International Journal of …, 2022 - mdpi.com
Background: Despite numerous studies of women having children later in life, evidence of
the relationship between maternal factors and newborn outcomes in Central and Eastern …

Predicting peripartum blood transfusion: focusing on pre-pregnancy characteristics

YT Ouh, KM Lee, KH Ahn, SC Hong, MJ Oh… - BMC Pregnancy and …, 2019 - Springer
Background Obstetric hemorrhage is one of the most common causes of obstetrical
morbidity and mortality, and transfusion is the most important management for hemorrhage …

Impact of Chronic Exposure to Endometriosis on Perinatal Outcomes: Establishment of a Mouse Model

M Elsherbini, K Koga, E Maki, K Kumasawa, E Satake… - Biomedicines, 2022 - mdpi.com
The purpose of this study was to establish a new mouse model of endometriosis that mimics
real-world women's health problems, in which women continue to be affected by …

Elevated Maternal Folate Status and Changes in Maternal Prolactin, Placental Lactogen and Placental Growth Hormone Following Folic Acid Food Fortification …

T Jankovic-Karasoulos, MD Smith, S Leemaqz… - Nutrients, 2023 - mdpi.com
Folic acid (FA) food fortification in Australia has resulted in a higher-than-expected intake of
FA during pregnancy. High FA intake is associated with increased insulin resistance and …

The effect of tauroursodeoxycholic acid (TUDCA) treatment on pregnancy outcomes and vascular function in a rat model of advanced maternal age

M Pasha, R Kirschenman, A Wooldridge, F Spaans… - Antioxidants, 2022 - mdpi.com
Advanced maternal age (≥ 35 years) increases the risk of vascular complications in
pregnancy that can result in fetal growth restriction and preeclampsia. Endoplasmic …

Maternal cardiometabolic factors and genetic ancestry influence epigenetic aging of the placenta

T Workalemahu, D Shrestha, SM Tajuddin… - … origins of health and …, 2021 - cambridge.org
Disruption of physiological aging of the placenta can lead to pregnancy complications and
increased risk for cardiometabolic diseases during childhood and adulthood. Maternal …