Background Estimation of the epidemiological burden of carotid atherosclerosis can serve
as a basis for prevention and management of cardiovascular disease. We aimed to provide …

While risk scores are invaluable tools for adapted preventive strategies, a significant gap
exists between predicted and actual event rates. Additional tools to further stratify the risk of …

Rationale: Machine learning may be useful to characterize cardiovascular risk, predict
outcomes, and identify biomarkers in population studies. Objective: To test the ability of …

Patients with chronic kidney disease (CKD) are at an increased risk of premature mortality,
mainly from cardiovascular causes. The association between CKD on hemodialysis and …

Background Metformin might reduce insulin requirement and improve glycaemia in patients
with type 1 diabetes, but whether it has cardiovascular benefits is unknown. We aimed to …

Carotid intima-media thickness (CIMT) has been shown to predict cardiovascular (CV) risk in
multiple large studies. Careful evaluation of CIMT studies reveals discrepancies in the …

Arterial remodeling refers to the structural and functional changes of the vessel wall that
occur in response to disease, injury, or aging. Vascular smooth muscle cells (VSMC) play a …

The carotid intima-media thickness (IMT) is a widely used surrogate marker for
atherosclerosis worldwide. The carotid IMT can be simply, noninvasively, and reproducibly …

Background—Presence of coronary artery calcium (CAC), carotid plaque, and increased
carotid intima-media thickness (IMT) may indicate elevated cardiovascular disease (CVD) …

Objective. The neutrophil‐to‐lymphocyte ratio (NLR) is an inexpensive and easily
measurable laboratory index indicating systemic inflammation, while the application of many …