Glial contributions to neuronal health and disease: new insights from Drosophila
MA Logan - Current opinion in neurobiology, 2017 - Elsevier
Highlights•Drosophila glia are strikingly similar to mammalian counterparts in form and
function.•Glial immune responses decline naturally with age.•Innate immune responses …
function.•Glial immune responses decline naturally with age.•Innate immune responses …
Inhibition of Sarco-Endoplasmic Reticulum Ca2+ ATPase Extends the Lifespan in C. elegans Worms
P García-Casas, J Arias-del-Val… - Frontiers in …, 2018 - frontiersin.org
The sarco-endoplasmic reticulum Ca2+-ATPase (SERCA) refills the endoplasmic reticulum
(ER) with Ca2+ up to the millimolar range and is therefore the main controller of the ER …
(ER) with Ca2+ up to the millimolar range and is therefore the main controller of the ER …
Metabolic signature of leukocyte telomere length in elite male soccer players
S Al-Muraikhy, M Sellami, AS Domling… - Frontiers in Molecular …, 2021 - frontiersin.org
Introduction: Biological aging is associated with changes in the metabolic pathways.
Leukocyte telomere length (LTL) is a predictive marker of biological aging; however, the …
Leukocyte telomere length (LTL) is a predictive marker of biological aging; however, the …
CTRP9 ameliorates cellular senescence via PGC‑1α/AMPK signaling in mesenchymal stem cells
Q Li, Z Zhu, C Wang, L Cai, J Lu… - International …, 2018 - spandidos-publications.com
Stroke is the second most common cause of death worldwide, and thus, it imposes great
financial burdens on both individuals and society. Mesenchymal stem cell (MSC) therapy is …
financial burdens on both individuals and society. Mesenchymal stem cell (MSC) therapy is …
Growth hormone receptor deficiency in humans associates to obesity, increased body fat percentage, a healthy brain and a coordinated insulin sensitivity
J Guevara-Aguirre, E Teran, D Lescano… - Growth Hormone & IGF …, 2020 - Elsevier
Background We have shown that subjects with Laron syndrome (LS) due to growth hormone
receptor deficiency (GHRD) and their relatives have comparable brain structure and …
receptor deficiency (GHRD) and their relatives have comparable brain structure and …
Pleiotropic influence of DNA methylation QTLs on physiological and ageing traits
ABSTRACT DNA methylation is influenced by genetic and non-genetic factors. Here, we
chart quantitative trait loci (QTLs) that modulate levels of methylation at highly conserved …
chart quantitative trait loci (QTLs) that modulate levels of methylation at highly conserved …
Shared genetic architecture between attention-deficit/hyperactivity disorder and lifespan
L Vilar-Ribó, J Cabana-Domínguez… - …, 2023 - nature.com
There is evidence linking ADHD to a reduced life expectancy. The mortality rate in
individuals with ADHD is twice that of the general population and it is associated with …
individuals with ADHD is twice that of the general population and it is associated with …
Microtubule regulators act in the nervous system to modulate fat metabolism and longevity through DAF‐16 in C. elegans
Microtubule (MT) regulation is involved in both neuronal function and the maintenance of
neuronal structure, and MT dysregulation appears to be a general downstream indicator and …
neuronal structure, and MT dysregulation appears to be a general downstream indicator and …
Metabolism of sleep and aging: Bridging the gap using metabolomics
A Sengupta, AM Weljie - Nutrition and Healthy Aging, 2019 - content.iospress.com
Sleep is a conserved behavior across the evolutionary timescale. Almost all known animal
species demonstrate sleep or sleep like states. Despite extensive study, the mechanistic …
species demonstrate sleep or sleep like states. Despite extensive study, the mechanistic …