The threat of antimicrobial resistance in developing countries: causes and control strategies

JA Ayukekbong, M Ntemgwa, AN Atabe - Antimicrobial Resistance & …, 2017 - Springer
The causes of antimicrobial resistance (AMR) in developing countries are complex and may
be rooted in practices of health care professionals and patients' behavior towards the use of …

Antimalarial drug toxicity: a review

HO AlKadi - Chemotherapy, 2007 - karger.com
Antimalarial drug toxicity is viewed differently depending upon whether the clinical indication
is for malaria treatment or prophylaxis. In the treatment of Plasmodium falciparum malaria …

An insight into the implementation of the global action plan on antimicrobial resistance in the WHO African region: A roadmap for action

CD Iwu, SM Patrick - International Journal of Antimicrobial Agents, 2021 - Elsevier
Abstract Introduction The Global Action Plan (GAP) on antimicrobial resistance (AMR)
delivers a 'One Health'strategy for the development of the national action plan. It encourages …

Chloroquine and sulfadoxine–pyrimethamine resistance in Sub-Saharan Africa—A review

AT Roux, L Maharaj, O Oyegoke, OP Akoniyon… - Frontiers in …, 2021 - frontiersin.org
Malaria is a great concern for global health and accounts for a large amount of morbidity and
mortality, particularly in Africa, with sub-Saharan Africa carrying the greatest burden of the …

Adherence to artemisinin-based combination therapy for the treatment of malaria: a systematic review of the evidence

K Banek, M Lalani, SG Staedke, D Chandramohan - Malaria journal, 2014 - Springer
Background Increasing access to and targeting of artemisinin-based combination therapy
(ACT) is a key component of malaria control programmes. To maximize efficacy of ACT and …

Plasmepsins as potential targets for new antimalarial therapy

K Ersmark, B Samuelsson… - Medicinal research …, 2006 - Wiley Online Library
Malaria is one of the major diseases in the world. Due to the rapid spread of parasite
resistance to available antimalarial drugs there is an urgent need for new antimalarials with …

High-efficiency transformation of Plasmodium falciparum by the lepidopteran transposable element piggyBac

B Balu, DA Shoue, MJ Fraser Jr… - Proceedings of the …, 2005 - National Acad Sciences
Functional analysis of the Plasmodium falciparum genome is restricted because of the
limited ability to genetically manipulate this important human pathogen. We have developed …

Genomewide analysis of the host response to malaria in Kenyan children

MJ Griffiths, MJ Shafi, SJ Popper… - Journal of Infectious …, 2005 - academic.oup.com
Malaria is a global problem, and there is a critical need for further understanding of the
disease process. When malarial parasites invade and develop within the bloodstream, they …

The potential for interactions between antimalarial and antiretroviral drugs

S Khoo, D Back, P Winstanley - Aids, 2005 - journals.lww.com
The rapid increase in access to antiretroviral therapy in developing countries has brought
with it new challenges. These include the unprecedented need for lifelong treatment for an …

Antimalarial drug quality in Africa

AA Amin, GO Kokwaro - Journal of clinical pharmacy and …, 2007 - Wiley Online Library
Background and objective: There are several reports of sub‐standard and counterfeit
antimalarial drugs circulating in the markets of developing countries; we aimed to review the …