[HTML][HTML] The biosynthesis of enzymatically oxidized lipids

AA Hajeyah, WJ Griffiths, Y Wang, AJ Finch… - Frontiers in …, 2020 - frontiersin.org
Enzymatically oxidized lipids are a specific group of biomolecules that function as key
signaling mediators and hormones, regulating various cellular and physiological processes …

[HTML][HTML] Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases

AN Saiyed, AR Vasavada, SRK Johar - Future Journal of Pharmaceutical …, 2022 - Springer
Background Researchers now have a new avenue to investigate when it comes to miRNA-
based therapeutics. miRNAs have the potential to be valuable biomarkers for disease …

[HTML][HTML] The role of CYP3A in health and disease

LS Klyushova, ML Perepechaeva, AY Grishanova - Biomedicines, 2022 - mdpi.com
CYP3A is an enzyme subfamily in the cytochrome P450 (CYP) superfamily and includes
isoforms CYP3A4, CYP3A5, CYP3A7, and CYP3A43. CYP3A enzymes are indiscriminate …

[HTML][HTML] MicroRNA as a potential therapeutic molecule in cancer

J Szczepanek, M Skorupa, A Tretyn - Cells, 2022 - mdpi.com
Small noncoding RNAs, as post-translational regulators of many target genes, are not only
markers of neoplastic disease initiation and progression, but also markers of response to …

[HTML][HTML] Long non-coding RNA in cervical cancer: From biology to therapeutic opportunity

J He, B Huang, K Zhang, M Liu, T Xu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Genome regions that do not for code for proteins are generally transcribed into long non-
coding RNAs. Growing evidence reveals that lncRNAs, defined as transcripts longer than …

[HTML][HTML] Role of non-coding-RNAs in response to environmental stressors and consequences on human health

V Miguel, S Lamas, C Espinosa-Diez - Redox biology, 2020 - Elsevier
Environmental risk factors, including physicochemical agents, noise and mental stress, have
a considerable impact on human health. This environmental exposure may lead to …

CoraL: interpretable contrastive meta-learning for the prediction of cancer-associated ncRNA-encoded small peptides

Z Li, J Jin, W He, W Long, H Yu, X Gao… - Briefings in …, 2023 - academic.oup.com
NcRNA-encoded small peptides (ncPEPs) have recently emerged as promising targets and
biomarkers for cancer immunotherapy. Therefore, identifying cancer-associated ncPEPs is …

Triclosan: Antimicrobial mechanisms, antibiotics interactions, clinical applications, and human health

P Shrestha, Y Zhang, WJ Chen… - Journal of Environmental …, 2020 - Taylor & Francis
The large-scale applications of Triclosan in industrial and household products have created
many health and environmental concerns. Despite the fears of its drug-resistance and other …

LncRNA regulation: New frontiers in epigenetic solutions to drug chemoresistance

Y Zhou, W Sun, Z Qin, S Guo, Y Kang, S Zeng… - Biochemical …, 2021 - Elsevier
Long-noncoding RNAs (lncRNAs) have been shown to participate in sensitizing or de-
sensitizing cancer cells to chemical drugs during cancer therapeutics. Notably, a plethora of …

SPENCER: a comprehensive database for small peptides encoded by noncoding RNAs in cancer patients

X Luo, Y Huang, H Li, Y Luo, Z Zuo… - Nucleic Acids …, 2022 - academic.oup.com
As an increasing number of noncoding RNAs (ncRNAs) have been suggested to encode
short bioactive peptides in cancer, the exploration of ncRNA-encoded small peptides …