Ellagic acid ameliorates lung damage in rats via modulating antioxidant activities, inhibitory effects on inflammatory mediators and apoptosis-inducing activities

A Aslan, YT Hussein, O Gok, S Beyaz, O Erman… - … Science and Pollution …, 2020 - Springer
Phytochemicals is considered one of the most effective and safe alternative therapy against
oxidative linked lung diseases. Ellagic acid (EA), an important component of fruits, nuts, and …

Cannabidiol and the canonical WNT/β-catenin pathway in glaucoma

A Vallée, Y Lecarpentier, JN Vallée - International Journal of Molecular …, 2021 - mdpi.com
Glaucoma is a progressive neurodegenerative disease which constitutes the main frequent
cause of irreversible blindness. Recent findings have shown that oxidative stress …

n-3 polyunsaturated fatty acids and their role in cancer chemoprevention

Z Gu, K Shan, H Chen, YQ Chen - Current pharmacology reports, 2015 - Springer
Polyunsaturated fatty acids (PUFAs), including omega-3 (n-3) and omega-6 (n-6) PUFAs,
are essential for human health. Recent research shows n-3 PUFAs and their mediators can …

Regulation of cell signaling pathways by dietary agents for cancer prevention and treatment

MK Pandey, SC Gupta, A Nabavizadeh… - Seminars in cancer …, 2017 - Elsevier
Although it is widely accepted that better food habits do play important role in cancer
prevention and treatment, how dietary agents mediate their effects remains poorly …

Pyrogens, a polypeptide produces fever by metabolic changes in hypothalamus: Mechanisms and detections

N Prajitha, SS Athira, PV Mohanan - Immunology letters, 2018 - Elsevier
Fever is one of the cardinal symptoms of onset of an infection or inflammation and is the
common clinical indicator for medical consultation in mammalian host worldwide. Simply …

[HTML][HTML] Lupane-type triterpenes and their anti-cancer activities against most common malignant tumors: A review

MH Cháirez-Ramírez, MR Moreno-Jiménez… - EXCLI …, 2016 - ncbi.nlm.nih.gov
In recent times, a great deal of interest has been motivated on plant derived compounds
known as nutraceuticals. These compounds exert important beneficial activities that improve …

PD-1 Independent Role of PD-L1 in Triple-Negative Breast Cancer Progression

D Alkaabi, K Arafat, S Sulaiman, AM Al-Azawi… - International journal of …, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is a type of breast malignancy characterized by a high
proliferative rate and metastatic potential leading to treatment failure, relapse, and poor …

NLRP3 inflammasome activation in human vestibular schwannoma: Implications for tumor-induced hearing loss

JE Sagers, MI Sahin, IS Moon, SG Ahmed… - Hearing research, 2019 - Elsevier
Vestibular schwannoma (VS) is the fourth most common intracranial tumor, arising from
neoplastic Schwann cells of the vestibular nerve and often causing debilitating …

The gut microbiota can orchestrate the signaling pathways in colorectal cancer

ALB Bennedsen, S Furbo, T Bjarnsholt, H Raskov… - Apmis, 2022 - Wiley Online Library
Current evidence suggests that bacteria contribute to the development of certain cancers,
such as colorectal cancer (CRC), partly by stimulating chronic inflammation. However, little …

[HTML][HTML] Quantitative visualization of hypoxia and proliferation gradients within histological tissue sections

M Zaidi, F Fu, D Cojocari, TD McKee… - … in Bioengineering and …, 2019 - frontiersin.org
The formation of hypoxic microenvironments within solid tumors is known to contribute to
radiation resistance, chemotherapy resistance, immune suppression, increased metastasis …