Identification of novel anti-inflammatory peptides from bee pollen (Apis mellifera) hydrolysate in lipopolysaccharide-stimulated RAW264.7 macrophages

T Saisavoey, P Sangtanoo, C Chanchao… - Journal of Apicultural …, 2021 - Taylor & Francis
Bee pollen protein was hydrolyzed using the commercial Alcalase, Flavourzyme and
Neutrase enzymes. The Neutrase hydrolysate formed from a 1: 1 (v/v) enzyme/substrate …

A weighty problem: metabolic perturbations and the obesity-cancer link

CH O'Flanagan, LW Bowers… - … molecular biology and …, 2015 - degruyter.com
Obesity is an established risk factor for several cancers, including breast, colon, endometrial,
ovarian, gastric, pancreatic and liver, and is increasingly a public health concern. Obese …

The ketogenic diet for the treatment of glioma: insights from genetic profiling

AC Scheck, MG Abdelwahab, KE Fenton, P Stafford - Epilepsy research, 2012 - Elsevier
Seizures, particularly first onset seizures in adults, are a diagnostic hallmark of brain tumors
(Giglio and Villano, 2010). Unfortunately, malignant brain tumors are almost uniformly fatal …

Combination of magnetic targeting with synergistic inhibition of NF-κB and glutathione via micellar drug nanomedicine enhances its anti-tumor efficacy

KA Elhasany, SN Khattab, AA Bekhit, DM Ragab… - European Journal of …, 2020 - Elsevier
Breast cancer is not only one of the most prevalent types of cancer, but also it is a prime
cause of death in women aged between 20 and 59. Although chemotherapy is the most …

[HTML][HTML] The paradox role of caspase cascade in ionizing radiation therapy

N Rahmanian, SJ Hosseinimehr, A Khalaj - Journal of biomedical science, 2016 - Springer
Radiotherapy alone or in combination with chemotherapy/surgery is widely used for
treatment of cancers. It reduces tumor growth and prevents metastasis. While ionizing …

Design, synthesis and biological evaluation of novel indanone containing spiroisoxazoline derivatives with selective COX-2 inhibition as anticancer agents

H Abolhasani, A Zarghi, TK Movahhed… - Bioorganic & Medicinal …, 2021 - Elsevier
Objective A new family of 3′-(Mono, di or tri-substituted phenyl)-4′-(4-(methylsulfonyl)
phenyl) spiroisoxazoline derivatives containing indanone spirobridge was designed …

Arachidonic acid actions on functional integrity and attenuation of the negative effects of palmitic acid in a clonal pancreatic β-cell line

DC Keane, HK Takahashi, S Dhayal… - Clinical …, 2011 - portlandpress.com
Chronic exposure of pancreatic β-cells to saturated non-esterified fatty acids can lead to
inhibition of insulin secretion and apoptosis. Several previous studies have demonstrated …

Effect of celecoxib on survival in patients with advanced non-small cell lung cancer: a double blind randomised clinical phase III trial (CYCLUS study) by the Swedish …

A Koch, B Bergman, E Holmberg, C Sederholm… - European journal of …, 2011 - Elsevier
Background Increased expression of cyclooxygenase-2 (COX-2) is common in non-small
cell lung cancer (NSCLC) and has been associated with poor prognosis. Experimental and …

Quercetin attenuates cell survival, inflammation, and angiogenesis via modulation of AKT signaling in murine T-cell lymphoma

AK Maurya, M Vinayak - Nutrition and cancer, 2017 - Taylor & Francis
ABSTRACT AKT signaling is important to maintaining normal physiology. Hyperactivation of
AKT signaling is frequent in cancer, which maintains a high oxidative state in a tumor …

Combined Effect of Moringa oleifera and Ionizing Radiation on Survival and Metastatic Activity of Pancreatic Cancer Cells

L Hagoel, A Vexler, L Kalich-Philosoph… - Integrative cancer …, 2019 - journals.sagepub.com
Background: Radiotherapy is one of the main treatments for malignancies. Radioresistance
is a major obstacle in this treatment, calling for new treatments to improve radiotherapy …