We review the recent biomedical detection developments of scanning near-field optical
microscopy (SNOM), focusing on scattering-type SNOM, atomic force microscope-based …

Despite the ubiquitous absorption of mid-infrared (IR) radiation by virtually all molecules that
belong to the major biomolecules groups (proteins, lipids, carbohydrates, nucleic acids), the …

Abrupt aggregation of amyloid β1‐42 (Aβ) peptide is a hallmark of Alzheimer's disease (AD),
a severe pathology that affects more than 44 million people worldwide. A growing body of …

Amyloid formation is a hallmark of many medical diseases including diabetes type 2,
Alzheimer's and Parkinson diseases. Under these pathological conditions, misfolded …

Lipid bilayers play an important role in the pathological assembly of amyloidogenic proteins
and peptides. This assembly yields oligomers and fibrils, which are highly toxic protein …

Amyloid oligomers and fibrils are protein aggregates that cause an onset and progression of
many neurodegenerative diseases, diabetes type 2 and systemic amyloidosis. Although a …

Phosphatidylserine (PS) in the plasma membrane plays an important role in cell signaling
and apoptosis. Cell degeneration is also linked to numerous amyloid diseases, pathologies …

Phosphatidic acid (PA) is a unique plasma membrane lipid that contains fatty acids (FAs)
with different lengths and degrees of unsaturation. Under physiological conditions, PA acts …

Abrupt aggregation of misfolded proteins is a hallmark of the large group of amyloid
pathologies that include diabetes type 2, Alzheimer and Parkinson's diseases. Protein …

The progressive accumulation of transthyretin (TTR), a small protein that transports
thyroxine, in various organs and tissues is observed upon transthyretin amyloidosis, a …