Vaccination and autoimmune disease: what is the evidence?
DC Wraith, M Goldman, PH Lambert - The Lancet, 2003 - thelancet.com
As many as one in 20 people in Europe and North America have some form of autoimmune
disease. These diseases arise in genetically predisposed individuals but require an …
disease. These diseases arise in genetically predisposed individuals but require an …
A complex interaction between drug allergy and viral infection
T Shiohara, Y Kano - Clinical reviews in allergy & immunology, 2007 - Springer
A relationship between viral infections and the simultaneous or subsequent development of
drug rashes has been observed in a number of clinical situations. We have recently …
drug rashes has been observed in a number of clinical situations. We have recently …
Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP
B Manoury, D Mazzeo, L Fugger, N Viner… - Nature …, 2002 - nature.com
Little is known about the processing of putative human autoantigens and why tolerance is
established to some T cell epitopes but not others. Here we show that a principal human …
established to some T cell epitopes but not others. Here we show that a principal human …
[HTML][HTML] An overall view of the most common experimental models for multiple sclerosis
S Dedoni, M Scherma, C Camoglio, C Siddi… - Neurobiology of …, 2023 - Elsevier
Multiple sclerosis (MS) is a complex chronic disease with an unknown etiology. It is
considered an inflammatory demyelinating and neurodegenerative disorder of the central …
considered an inflammatory demyelinating and neurodegenerative disorder of the central …
Selection and fine-tuning of the autoimmune T-cell repertoire
SM Anderton, DC Wraith - Nature Reviews Immunology, 2002 - nature.com
The immune system must avoid aggressive T-cell responses against self-antigens. But,
paradoxically, exposure to self-peptides seems to have an important role in positive …
paradoxically, exposure to self-peptides seems to have an important role in positive …
Blocking stroke-induced immunodeficiency increases CNS antigen-specific autoreactivity but does not worsen functional outcome after experimental stroke
C Römer, O Engel, K Winek, S Hochmeister… - Journal of …, 2015 - Soc Neuroscience
Stroke-induced immunodepression (SIDS) is an essential cause of poststroke infections.
Pharmacological inhibition of SIDS appears promising in preventing life-threatening …
Pharmacological inhibition of SIDS appears promising in preventing life-threatening …
Sensitization to brain antigens after stroke is augmented by lipopolysaccharide
KJ Becker, DL Kindrick, MP Lester… - Journal of Cerebral …, 2005 - journals.sagepub.com
After stroke, the blood–brain barrier is transiently disrupted, allowing leukocytes to enter the
brain and brain antigens to enter the peripheral circulation. This encounter of normally …
brain and brain antigens to enter the peripheral circulation. This encounter of normally …
Alopecia areata: pathogenesis and potential for therapy
W Lu, J Shapiro, M Yu, A Barekatain, B Lo… - Expert reviews in …, 2006 - cambridge.org
Although the complete picture for alopecia areata (AA) pathogenesis has yet to be
determined, recent research has made much progress in our understanding of the disease …
determined, recent research has made much progress in our understanding of the disease …
[PDF][PDF] Vaccination may be associated with autoimmune diseases
M Tishler, Y Shoenfeld - IMAJ-RAMAT GAN-., 2004 - talkingaboutthescience.com
Autoimmune diseases affect as many as 1 in 10 people in Europe and North America.
Although the prevalence of most diseases is quite low, their individual incidence has greatly …
Although the prevalence of most diseases is quite low, their individual incidence has greatly …
Lipopolysaccharide injection induces relapses of experimental autoimmune encephalomyelitis in nontransgenic mice via bystander activation of autoreactive CD4+ …
A Nogai, V Siffrin, K Bonhagen, CF Pfueller… - The Journal of …, 2005 - journals.aai.org
Infections sometimes associate with exacerbations of autoimmune diseases through
pathways that are poorly understood. Ag-specific mechanisms such as cross-reactivity …
pathways that are poorly understood. Ag-specific mechanisms such as cross-reactivity …