Exosomes: cell-derived nanoplatforms for the delivery of cancer therapeutics

H Kim, EH Kim, G Kwak, SG Chi, SH Kim… - International journal of …, 2020 - mdpi.com
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …

Endosomal signalling via exosome surface TGFβ-1

GV Shelke, Y Yin, SC Jang, C Lässer… - Journal of …, 2019 - Taylor & Francis
Extracellular vesicles such as exosomes convey biological messages between cells, either
by surface-to-surface interaction or by shuttling of bioactive molecules to a recipient cell's …

Biological features of extracellular vesicles and challenges

Y Zeng, Y Qiu, W Jiang, J Shen, X Yao, X He… - Frontiers in Cell and …, 2022 - frontiersin.org
Extracellular vesicles (EVs) are vesicles with a lipid bilayer membrane on the outside, which
are widely found in various body fluids and contain biological macromolecules such as …

[HTML][HTML] The pivotal roles of exosomes derived from endogenous immune cells and exogenous stem cells in myocardial repair after acute myocardial infarction

YY Xiong, ZT Gong, RJ Tang, YJ Yang - Theranostics, 2021 - ncbi.nlm.nih.gov
Acute myocardial infarction (AMI) is one of the leading causes of mortality around the world,
and the inflammatory response plays a pivotal role in the progress of myocardial necrosis …

Immune cell-derived extracellular vesicles–new strategies in cancer immunotherapy

P Yang, Y Peng, Y Feng, Z Xu, P Feng, J Cao… - Frontiers in …, 2021 - frontiersin.org
Immune cell-derived extracellular vesicles (EVs) have increasingly become the focus of
research due to their unique characteristics and bioinspired applications. They are lipid …

Exosome-integrated titanium oxide nanotubes for targeted bone regeneration

F Wei, M Li, R Crawford, Y Zhou, Y Xiao - Acta biomaterialia, 2019 - Elsevier
Exosomes are extracellular nanovesicles that play an important role in cellular
communication. The modulatory effects of bone morphogenetic protein 2 (BMP2) on …

Immune cell-derived exosomes in the cancer-immunity cycle

W Yan, S Jiang - Trends in cancer, 2020 - cell.com
Cells can communicate through extracellular vesicle (EV) secretion and uptake. Exosomes
are lipid bilayer-enclosed EVs of 30–150 nm in diameter, which can transfer RNA, functional …

Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells

CH Wu, J Li, L Li, J Sun, M Fabbri… - Journal of …, 2019 - Taylor & Francis
Extracellular vesicles (EVs) are secreted membrane vesicles, which play complex
physiological and pathological functions in intercellular communication. Recently, we …

Specific decrease in B-cell-derived extracellular vesicles enhances post-chemotherapeutic CD8+ T cell responses

F Zhang, R Li, Y Yang, C Shi, Y Shen, C Lu, Y Chen… - Immunity, 2019 - cell.com
Systemic immunosuppression greatly affects the chemotherapeutic antitumor effect. Here,
we showed that CD19+ extracellular vesicles (EVs) from B cells through CD39 and CD73 …

Multiparametric analysis of circulating exosomes and other small extracellular vesicles by advanced imaging flow cytometry

S Mastoridis, GM Bertolino, G Whitehouse… - Frontiers in …, 2018 - frontiersin.org
Extracellular vesicles (EVs) are responsible for a multitude of physiological functions,
including immunomodulation. A heterogenous mixture of small EV (sEV) subsets, including …