Extracellular vesicles as mediators of cellular crosstalk between immune system and kidney graft

M Quaglia, S Dellepiane, G Guglielmetti… - Frontiers in …, 2020 - frontiersin.org
Extracellular vesicles (EVs) are known immune-modulators exerting a critical role in kidney
transplantation (KT). EV bioactive cargo includes graft antigens, costimulatory/inhibitory …

Extracellular vesicles as an advanced delivery biomaterial for precision cancer immunotherapy

S Ruan, Z Greenberg, X Pan, P Zhuang… - Advanced …, 2022 - Wiley Online Library
In recent years, cancer immunotherapy has been observed in numerous preclinical and
clinical studies for showing benefits. However, due to the unpredictable outcomes and low …

The impact of immune cell-derived exosomes on immune response initiation and immune system function

F Tavasolian, AZ Hosseini, M Rashidi… - Current …, 2021 - ingentaconnect.com
Exosomes are small extracellular vesicles that pass genetic material between various cells
to modulate or alter their biological function. The role of exosomes is to communicate with …

Multifunctional DNA‐Based Hydrogel Promotes Diabetic Alveolar Bone Defect Reconstruction

G Peng, W Li, L Peng, R Li, Z Wang, Y Zhou, L Gou… - Small, 2024 - Wiley Online Library
Diabetic alveolar bone defect (DABD) causes persistent bacterial infection, prolonged
inflammation, and delayed bone healing, making it a considerable clinical challenge. In this …

Extracellular vesicles and immunity: at the crossroads of cell communication

N Aloi, G Drago, S Ruggieri, F Cibella… - International journal of …, 2024 - mdpi.com
Extracellular vesicles (EVs), comprising exosomes and microvesicles, are small
membranous structures secreted by nearly all cell types. They have emerged as crucial …

MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme …

XS Ren, Y Tong, Y Qiu, C Ye, N Wu… - Journal of …, 2020 - Taylor & Francis
Proliferation of vascular smooth muscle cells (VSMCs) plays crucial roles in vascular
remodelling and stiffening in hypertension. Vascular adventitial fibroblasts are a key …

Macrophage-derived small extracellular vesicles promote biomimetic mineralized collagen-mediated endogenous bone regeneration

A Liu, S Jin, C Fu, S Cui, T Zhang, L Zhu… - International journal of …, 2020 - nature.com
Macrophages play an important role in material-related immune responses and bone
formation, but the functionality of macrophage-derived extracellular vesicles (EVs) in …

T lymphocyte and CAR-T cell-derived extracellular vesicles and their applications in cancer therapy

V Calvo, M Izquierdo - Cells, 2022 - mdpi.com
Extracellular vesicles (EV) are a very diverse group of cell-derived vesicles released by
almost all kind of living cells. EV are involved in intercellular exchange, both nearby and …

Advances of engineered extracellular vesicles-based therapeutics strategy

H Komuro, S Aminova, K Lauro… - Science and Technology …, 2022 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous population of lipid bilayer membrane-
bound vesicles which encapsulate bioactive molecules, such as nucleic acids, proteins, and …

[HTML][HTML] Engineered exosomes for cancer theranostics: Next-generation tumor targeting

VP Chavda, VV Sugandhi, CV Pardeshi, RJ Patil… - Journal of Drug Delivery …, 2023 - Elsevier
Exosomes are multivesicular bodies of which the plasma membrane fuse to release the
caring moiety into the surrounding body fluids. They are best known for their function in …