Therapeutic potential of exosomes in pulmonary fibrosis

L Xie, Y Zeng - Frontiers in Pharmacology, 2020 - frontiersin.org
Pulmonary fibrosis is closely associated with the recruitment of fibroblasts from capillary
vessels with damaged endothelial cells, the epithelial mesenchymal transition (EMT) of type …

Living cells and cell-derived vesicles: a trojan horse technique for brain delivery

A Ou, Y Wang, J Zhang, Y Huang - Pharmaceutics, 2023 - mdpi.com
Brain diseases remain a significant global healthcare burden. Conventional
pharmacological therapy for brain diseases encounters huge challenges because of the …

Extracellular vesicles and lipoproteins–Smart messengers of blood cells in the circulation

PHD Nguyen, AH Le, JSQ Pek, TT Pham… - Journal of …, 2022 - Wiley Online Library
Blood cell‐derived extracellular vesicles (BCEVs) and lipoproteins are the major circulating
nanoparticles in blood that play an important role in intercellular communication. They have …

[HTML][HTML] Immunoregulatory functions and therapeutic potential of natural killer cell-derived extracellular vesicles in chronic diseases

S He, L Su, H Hu, H Liu, J Xiong, X Gong… - Frontiers in …, 2024 - frontiersin.org
Extracellular vesicles (EVs) have been proven to play a significant immunoregulatory role in
many chronic diseases, such as cancer and immune disorders. Among them, EVs derived …

Extracellular vesicles, news about their role in immune cells: physiology, pathology and diseases

J Meldolesi - Clinical & Experimental Immunology, 2019 - academic.oup.com
Two types of extracellular vesicles (EVs), exosomes and ectosomes, are generated and
released by all cells, including immune cells. The two EVs appear different in many …

Viral antigens detectable in CSF exosomes from patients with retrovirus associated neurologic disease: functional role of exosomes

MR Anderson, ML Pleet, Y Enose-Akahata… - Clinical and translational …, 2018 - Springer
Background HTLV-1 infects over 20 million people worldwide and causes a progressive
neuroinflammatory disorder in a subset of infected individuals called HTLV-1 associated …

The functional roles of exosomes-derived long non-coding RNA in human cancer

F Chen, N Wang, HY Tan, W Guo… - Cancer Biology & …, 2019 - Taylor & Francis
Cancer is one of the most pervasive causes of morbidity and mortality worldwide regardless
of the fact that a majority of therapeutic strategies have been constantly invented. The …

Small extracellular vesicles isolated from serum may serve as signal-enhancers for the monitoring of CNS tumors

G Dobra, M Bukva, Z Szabo, B Bruszel… - International Journal of …, 2020 - mdpi.com
Liquid biopsy-based methods to test biomarkers (eg, serum proteins and extracellular
vesicles) may help to monitor brain tumors. In this proteomics-based study, we aimed to …

Proteome analysis of human natural killer cell derived extracellular vesicles for identification of anticancer effectors

JW Choi, S Lim, JH Kang, SH Hwang, KC Hwang… - Molecules, 2020 - mdpi.com
Cancer immunotherapy is a clinically validated therapeutic modality for cancer and has
been rapidly advancing in recent years. Adoptive transfer of immune cells such as T cells …

Monitoring therapy efficiency in cancer through extracellular vesicles

I Stevic, G Buescher, FL Ricklefs - Cells, 2020 - mdpi.com
Extracellular vesicles (EVs) are a heterogeneous group of membrane-enclosed vesicles
made of a phospholipid bilayer and are secreted by all cell types. EVs are present in a …