[HTML][HTML] Extracellular vesicles in the tumour microenvironment: eclectic supervisors

C Cavallari, G Camussi, MF Brizzi - International journal of molecular …, 2020 - mdpi.com
The tumour microenvironment (TME) plays a crucial role in the regulation of cell survival and
growth by providing inhibitory or stimulatory signals. Extracellular vesicles (EV) represent …

[HTML][HTML] Antitumor immunity: Role of NK cells and extracellular vesicles in cancer immunotherapy

AE Prokopeva, CC Emene, MO Gomzikova - Current Issues in Molecular …, 2023 - mdpi.com
The immune system plays a crucial role in recognizing and eliminating altered tumor cells.
However, tumors develop mechanisms to evade the body's natural immune defenses …

[HTML][HTML] A new role for extracellular vesicles: how small vesicles can feed tumors' big appetite

I Lazar, E Clement, C Attane, C Muller, L Nieto - Journal of lipid research, 2018 - ASBMB
Cancer cells must adapt their metabolism in order to meet the energy requirements for cell
proliferation, survival in nutrient-deprived environments, and dissemination. In particular, FA …

[HTML][HTML] Immunoregulatory effects of mitochondria transferred by extracellular vesicles

Z She, M Xie, M Hun, AS Abdirahman, C Li… - Frontiers in …, 2021 - frontiersin.org
Mitochondria participate in immune regulation through various mechanisms, such as
changes in the mitochondrial dynamics, as metabolic mediators of the tricarboxylic acid …

[HTML][HTML] Regulatory role of immune cell-derived extracellular vesicles in cancer: the message is in the envelope

C Li, H Donninger, J Eaton, K Yaddanapudi - Frontiers in Immunology, 2020 - frontiersin.org
Extracellular vesicles (EVs) are a heterogenous group of membrane-surrounded structures.
Besides serving as a harbor for the unwanted material exocytosed by cells, EVs play a …

Immunomodulatory properties of extracellular vesicles in the dialogue between placental and immune cells

RR Favaro, JM Murrieta‐Coxca… - American Journal of …, 2021 - Wiley Online Library
Extracellular vesicle (EV)‐mediated communication has been implicated in the cooperative
alliance between trophoblast and immune cells toward maternal tolerance and placentation …

CAR-T cell therapy: a game-changer in cancer treatment and beyond

K Utkarsh, N Srivastava, S Kumar, A Khan… - Clinical and …, 2024 - Springer
In recent years, cancer has become one of the primary causes of mortality, approximately 10
million deaths worldwide each year. The most advanced, chimeric antigen receptor (CAR) T …

[HTML][HTML] Theragnostic applications of mammal and plant-derived extracellular vesicles: latest findings, current technologies, and prospects

NB Ali, AF Abdull Razis, DJ Ooi, KW Chan, N Ismail… - Molecules, 2022 - mdpi.com
The way cells communicate is not fully understood. However, it is well-known that
extracellular vesicles (EVs) are involved. Researchers initially thought that EVs were used …

Cellular Membrane Components‐Mediated Cancer Immunotherapeutic Platforms

S Yun, S Kim, K Kim - Macromolecular Bioscience, 2023 - Wiley Online Library
Immune cell engineering is an active field of ongoing research that can be easily applied to
nanoscale biomedicine as an alternative to overcoming limitations of nanoparticles. Cell …

[HTML][HTML] Polymers in engineering extracellular vesicle mimetics: current status and prospective

X Wei, S Liu, Y Cao, Z Wang, S Chen - Pharmaceutics, 2023 - mdpi.com
The maintenance of a high delivery efficiency by traditional nanomedicines during cancer
treatment is a challenging task. As a natural mediator for short-distance intercellular …